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Anti-S100B Antibody (7I446)

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货号 TMAB-12461

Anti-S100B Antibody (7I446) 是一种 Rabbit 抗体，靶向 S100B。Anti-S100B Antibody (7I446) 可用于 WB,IHC-P,IHC-Fr,IF,FCM,ICC/IF。

Anti-S100B Antibody (7I446)

Anti-S100B Antibody (7I446)

一键复制产品信息
Rating icon 还可以
货号 TMAB-12461

Anti-S100B Antibody (7I446) 是一种 Rabbit 抗体，靶向 S100B。Anti-S100B Antibody (7I446) 可用于 WB,IHC-P,IHC-Fr,IF,FCM,ICC/IF。

规格价格库存数量
25 μL
¥ 785
5日内发货
50 μL
¥ 1,390
5日内发货
100 μL
¥ 2,485
5日内发货
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产品介绍

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产品描述
Anti-S100B Antibody (7I446) is a Rabbit antibody targeting S100B. Anti-S100B Antibody (7I446) can be used in WB,IHC-P,IHC-Fr,IF,FCM,ICC/IF.
Ig Type
IgG
克隆号
7I446
反应种属
Human,Mouse,Rat
应用WBIHC-PIHC-FrIFFCMICC/IF
推荐剂量
WB: 1:500-2000; IHC-P: 1:50-200; IHC-Fr: 1:50-200; IF: 1:50-200; FCM: 1:50-100; ICC/IF: 1:50-200
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Nucleus.
组织特异性Although predominant among the water-soluble brain proteins, S100 is also found in a variety of other tissues.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景S100 beta is a member of the S100 family of proteins containing 2 EF-hand calcium binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 21q22.3. This protein may function in neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes.
抗原信息
免疫原
A synthesized peptide: human S100B
抗原种属
Human
基因名称
S100B
基因ID
6285
蛋白名称
Protein S100-B
Uniprot ID
P04271
功能
Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling.
化学信息
分子量Theoretical: 10 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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