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Anti-EFNB2 Monoclonal Antibody

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Anti-EFNB2 Monoclonal Antibody
产品编号 TMAZ-0210
别名 HTK ligand, Ephrin-B2, EPH-related receptor tyrosine kinase ligand 5

Anti-EFNB2 Monoclonal Antibody is a humanized rabbit antibody targeting EFNB2. Anti-EFNB2 Monoclonal Antibody can be used in ELISA, FCM.

Anti-EFNB2 Monoclonal Antibody

Anti-EFNB2 Monoclonal Antibody

Rating icon 还可以
Anti-EFNB2 Monoclonal Antibody
产品编号 TMAZ-0210 别名 HTK ligand, Ephrin-B2, EPH-related receptor tyrosine kinase ligand 5

Anti-EFNB2 Monoclonal Antibody is a humanized rabbit antibody targeting EFNB2. Anti-EFNB2 Monoclonal Antibody can be used in ELISA, FCM.

规格价格库存数量
25 μg
¥ 2,577
7日内发货
50 μg
¥ 3,092
7日内发货
100 μg
¥ 4,328
7日内发货
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TargetMol 的所有产品仅用作科学研究或药证申报,不能被用于人体,我们不向个人提供产品和服务。请您遵守承诺用途,不得违反法律法规规定用于任何其他用途。
实验操作小课堂
常见问题解答
化合物带有盐酸盐离子、硫酸盐离子等是否和其本身有什么区别?盐形式和游离态有什么区别?
盐和非盐形式化合物的活性分子是一样的,在生物实验中起到的效果也一致,活性和使用方法都是一样的。只是由于呈盐不同,物理性质比如溶解度会有差异。建议您根据溶解、实验需求进行选择。
如何选择某个靶点的特异性或总的抑制剂?特异性和非特异性的区别是什么?
抑制剂按照特异性分为广谱 pan 和特异性 selective 两种。Pan 为某个靶点总的抑制剂,对所有亚型或整个家族的成员都有抑制作用。Selective 抑制剂针对某个蛋白激酶的某个亚型或家族中某个成员抑制率特别高或有特异性抑制作用。 一般评价一个抑制剂的抑制效率主要看 IC50 值,IC50 值越低,说明抑制剂效率越高。建议您根据以上几个特征进行综合选择,也可联系技术帮您推荐相关抑制剂。
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选择批次:
浓度:0.4 mg/mL
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产品介绍

生物活性
产品描述
Anti-EFNB2 Monoclonal Antibody is a humanized rabbit antibody targeting EFNB2. Anti-EFNB2 Monoclonal Antibody can be used in ELISA, FCM.
别名HTK ligand, Ephrin-B2, EPH-related receptor tyrosine kinase ligand 5
Ig Type
Rabbit monoclonal IgG
交叉反应
Human
验证活性
Flow cytometry analysis of EFNB2 overexpressed 429F cells with TMAZ-0210, followed by goat anti-rabbit IgG-ABflo 647 (red line). The isotype control is rabbit IgG (black line).
应用
推荐剂量
0.1-0.2 μg/10E6 cells for FCM; 1 ng/μl for ELISA
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Single-pass type I membrane
构建方式This antibody was produced from a rabbit immunized with purified, recombinant human extracellular domain of EFNB2 protein.
纯化方式Protein A Affinity Purified
性状Liquid
缓冲液0.22 μm filtered solution in PBS.
纯度> 95% as determined by SDS-PAGE.
研究背景Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Binds to receptor tyrosine kinase including EPHA4, EPHA3 and EPHB4. Together with EPHB4 plays a central role in heart morphogenesis and angiogenesis through regulation of cell adhesion and cell migration. EPHB4-mediated forward signaling controls cellular repulsion and segregation from EFNB2-expressing cells. May play a role in constraining the orientation of longitudinally projecting axons|(Microbial infection) Acts as a receptor for Hendra virus and Nipah virus
偶联与修饰
偶联
Unconjugated
其他可选修饰符
Biotin
可提供抗体种类
2
抗原信息
免疫原
EFNB2
抗原种属
Human
基因ID
Uniprot ID
研究领域
Cytokines
化学信息
分子量150 kDa
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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