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Anti-GDF-6 Polyclonal Antibody
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产品编号 TMAB-00758
Anti-GDF-6 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 GDF-6。Anti-GDF-6 Polyclonal Antibody 可用于 WB。
Anti-GDF-6 Polyclonal Antibody
Anti-GDF-6 Polyclonal Antibody
还可以产品编号 TMAB-00758
Anti-GDF-6 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 GDF-6。Anti-GDF-6 Polyclonal Antibody 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,160 | 5日内发货 | |
| 100 μL | ¥ 1,960 | 5日内发货 | |
| 200 μL | ¥ 2,795 | 5日内发货 |
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产品介绍
生物活性
抗原信息
| 产品描述 | Anti-GDF-6 Polyclonal Antibody is a Rabbit antibody targeting GDF-6. Anti-GDF-6 Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| 交叉反应 | Human (predicted:Mouse,Rat,Dog,Cow,Horse,Rabbit) |
| 验证活性 | Sample: U251 (Human) Cell Lysate at 30 μg Primary: Anti-GDF6 (TMAB-00758) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 14 kDa Observed band size: 48 kDa |
| 应用 | |
| 推荐剂量 | WB: 1:500-2000 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Secreted |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究背景 | Growth/differentiation factors (GDFs) are members of the TGF superfamily (1,2). Members of the TGF superfamily are involved in embryonic development and adult tissue homeostasis (1). GDF-1 expression is almost exclusively restricted to the central nervous system and mediates cell differentiation events during embryonic development (3). Neither GDF-3 (Vgr-2) nor GDF-9 contains the conserved cysteine residue which is found in most other TGF superfamily members. GDF-3 is detectable in bone marrow, spleen, thymus and adipose tissue, whereas GDF-9 has only been detected in ovary (4). GDF-5 (also designated CDMP-1) has been shown to induce activation of plasminogen activator, thereby inducing angiogenesis. It is predominantly expressed in long bones during fetal embryonic development and is involved in bone formation. (5). GDF-5 mutations have been identified in mice with the mutation brachypodism (bp), a mutation which affects the length and number of bones in limbs (6). GDF-6 and GDF-7 are closely related to GDF-5 (6). GDF-8 has been shown to be a negative regulator of skeletal muscle mass (1). |
| 免疫原 | KLH conjugated synthetic peptide: human GDF6 |
| 抗原种属 | Human |
| 基因ID | |
| Uniprot ID | |
| 研究领域 | Neurogenesis,Visual system,TGF |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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