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顶部产品介绍偶联与修饰抗原信息储存和溶解信息计算器

Anti-EPAS1 Antibody (4H347)

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货号 TMAH-00395

别名 PASD2, PAS domain-containing protein 2, MOP2, Member of PAS protein 2, Hypoxia-inducible factor 2-alpha, HLF, HIF2-alpha, HIF-2-alpha, HIF2A, HIF-1-alpha-like factor, EPAS-1, Endothelial PAS domain-containing protein 1, Class E basic helix-loop-helix protein 73, bHLHe73, Basic-helix-loop-helix-PAS protein MOP2

Anti-EPAS1 Antibody (4H347) 是一种抗体，靶向 EPAS1。Anti-EPAS1 Antibody (4H347) 可用于 ELISA,IF。

Anti-EPAS1 Antibody (4H347)

Anti-EPAS1 Antibody (4H347)

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货号 TMAH-00395 别名 PASD2, PAS domain-containing protein 2, MOP2, Member of PAS protein 2, Hypoxia-inducible factor 2-alpha, HLF, HIF2-alpha, HIF-2-alpha, HIF2A, HIF-1-alpha-like factor, EPAS-1, Endothelial PAS domain-containing protein 1, Class E basic helix-loop-helix protein 73, bHLHe73, Basic-helix-loop-helix-PAS protein MOP2

Anti-EPAS1 Antibody (4H347) 是一种抗体，靶向 EPAS1。Anti-EPAS1 Antibody (4H347) 可用于 ELISA,IF。

规格价格库存数量
50 μL
¥ 1,315
5日内发货
100 μL
¥ 2,190
5日内发货
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产品介绍

生物活性
产品描述
Anti-EPAS1 Antibody (4H347) is an antibody targeting EPAS1. Anti-EPAS1 Antibody (4H347) can be used in ELISA,IF.
别名PASD2, PAS domain-containing protein 2, MOP2, Member of PAS protein 2, Hypoxia-inducible factor 2-alpha, HLF, HIF2-alpha, HIF-2-alpha, HIF2A, HIF-1-alpha-like factor, EPAS-1, Endothelial PAS domain-containing protein 1, Class E basic helix-loop-helix protein 73, bHLHe73, Basic-helix-loop-helix-PAS protein MOP2
Ig Type
Rabbit IgG
克隆号
4H347
反应种属
Human
验证活性
Immunofluorescence staining of Hela Cells with TMAH-00395 at 1:50, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeated by 0.2% TritonX-100, and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. Nuclear DNA was labeled in blue with DAPI. The secondary antibody was FITC-conjugated AffiniPure Goat Anti-Rabbit IgG (H+L).
应用ELISAIF
推荐剂量
IF:1:20-1:200.
抗体种类
Monoclonal
亚细胞定位Nucleus. Nucleus speckle.
组织特异性Expressed in most tissues, with highest levels in placenta, lung and heart. Selectively expressed in endothelial cells.
构建方式Recombinant Antibody
纯化方式Affinity-chromatography
性状Liquid
缓冲液Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
研究背景Transcription factor involved in the induction of oxygen regulated genes. Heterodimerizes with ARNT; heterodimer binds to core DNA sequence 5'-TACGTG-3' within the hypoxia response element (HRE) of target gene promoters. Regulates the vascular endothelial growth factor (VEGF) expression and seems to be implicated in the development of blood vessels and the tubular system of lung. May also play a role in the formation of the endothelium that gives rise to the blood brain barrier. Potent activator of the Tie-2 tyrosine kinase expression. Activation requires recruitment of transcriptional coactivators such as CREBBP and probably EP300. Interaction with redox regulatory protein APEX1 seems to activate CTAD.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
A synthetic peptide: Human HIF-2 alpha
抗原种属
Human
基因名称
EPAS1
基因ID
2034
Uniprot ID
Q99814
研究领域
Epigenetics and Nuclear Signaling, Cancer, Cardiovascular, Metabolism
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

  • 稀释 计算器
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