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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-JNK3/MAPK10 Polyclonal Antibody

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货号 TMAB-07883

Anti-JNK3/MAPK10 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 JNK3/MAPK10。Anti-JNK3/MAPK10 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-JNK3/MAPK10 Polyclonal Antibody

Anti-JNK3/MAPK10 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-07883

Anti-JNK3/MAPK10 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 JNK3/MAPK10。Anti-JNK3/MAPK10 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

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产品描述
Anti-JNK3/MAPK10 Polyclonal Antibody is a Rabbit antibody targeting JNK3/MAPK10. Anti-JNK3/MAPK10 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Mouse,Rat (predicted:Human,Chicken,Dog,Pig,Cow,Rabbit)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Membrane; Lipid-anchor. Nucleus. Note=Palmitoylation regulates MAPK10 trafficking to cytoskeleton.
组织特异性Specific to a subset of neurons in the nervous system. Present in the hippocampus and areas, cerebellum, striatum, brain stem, and weakly in the spinal cord. Very weak expression in testis and kidney.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景MAPK10 (JNK3) is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This protein is a neuron-specific form of c-Jun N-terminal kinases (JNKs). Through its phosphorylation and nuclear localization, this kinase plays regulatory roles in the signaling pathways of neuronal apoptosis. Beta-arrestin 2, a receptor-regulated MAP kinase scaffold protein, is found to interact with and stimulate the phosphorylation of this kinase by MAP kinase kinase 4 (MKK4). Cyclin-dependent kianse 5 (CDK5) can phosphorylate and inhibit the activity of this kinase, which may be important in preventing neuronal apoptosis. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.
抗原信息
免疫原
KLH conjugated synthetic peptide: human JNK3/MAPK10
抗原种属
Human
基因名称
MAPK10
基因ID
5602
蛋白名称
Mitogen-activated protein kinase 10
Uniprot ID
P53779
化学信息
分子量Theoretical: 53 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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