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Anti-Ficolin 1/FCN1 Antibody (4Q321)
还可以产品编号 TMAY-01342
Anti-Ficolin 1/FCN1 Antibody (4Q321) 是一种 Mouse 抗体，靶向 Ficolin 1/FCN1。Anti-Ficolin 1/FCN1 Antibody (4Q321) 可用于 ELISA(Cap)。
Anti-Ficolin 1/FCN1 Antibody (4Q321)
Anti-Ficolin 1/FCN1 Antibody (4Q321)
还可以产品编号 TMAY-01342
Anti-Ficolin 1/FCN1 Antibody (4Q321) 是一种 Mouse 抗体，靶向 Ficolin 1/FCN1。Anti-Ficolin 1/FCN1 Antibody (4Q321) 可用于 ELISA(Cap)。
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产品介绍
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偶联与修饰
抗原信息
| 产品描述 | Anti-Ficolin 1/FCN1 Antibody (4Q321) is a Mouse antibody targeting Ficolin 1/FCN1. Anti-Ficolin 1/FCN1 Antibody (4Q321) can be used in ELISA(Cap). |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 4Q321 |
| 交叉反应 | Human |
| 应用 | ELISA(Cap) |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human FCN1 / FCNA (rh FCN1 / FCNA; TMPY-01028; NP_001994.2; Met1-Ala326). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS with 10% Trehalose, 0.02% Tween 80, pH7.0 |
| 研究背景 | Ficolins are humoral molecules of the innate immune systems which recognize carbohydrate molecules on pathogens, apoptotic and necrotic cells. The Ficolin family of proteins are characterized by the presence of a leader peptide, a short N-terminal segment, followed by a collagen-like region, and a C-terminal fibrinogen-like domain. Ficolins are humoral molecules of the innate immune systems which recognize carbohydrate molecules on pathogens, apoptotic and necrotic cells. Three Ficolins have been identified in humans: L-Ficolin, H-Ficolin and M-Ficolin (also referred to as Ficolin-2, -3 and -1, respectively). They are soluble oligomeric defence proteins with lectin-like activity and they are structurally similar to the human collectins, mannan-binding lectin (MBL) and surfactant protein A and D. Dysfunction or abnormal expressions of Ficolins may involved in the pathogenesis of human diseases including infectious and inflammatory diseases, autoimmune disease and clinical syndrome of preeclampsia. They are soluble oligomeric defence proteins with lectin-like activity and they are structurally similar to the human collectins, mannan-binding lectin (MBL) and surfactant protein A and D. Upon recognition of the infectious agent, the Ficolins act through two distinct routes: initiate the lectin pathway of complement activation through attached serine proteases (MASPs), and a primitive opsonophagocytosis thus limiting the infection and concurrently orchestrating the subsequent adaptive clonal immune response. Ficolin-1 (FCN1) is predominantly expressed in the peripheral blood leukocytes. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human FCN1 / FCNA Protein (TMPY-01028) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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