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Anti-ALDH7A1 Antibody-FITC (5P692)

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产品编号 TMAY-01933F

Anti-ALDH7A1 Antibody-FITC (5P692) 是一种 FITC-conjugated Rabbit 抗体,靶向 ALDH7A1。Anti-ALDH7A1 Antibody-FITC (5P692) 可用于 FCM。

Anti-ALDH7A1 Antibody-FITC (5P692)

Anti-ALDH7A1 Antibody-FITC (5P692)

Rating icon 还可以
产品编号 TMAY-01933F

Anti-ALDH7A1 Antibody-FITC (5P692) 是一种 FITC-conjugated Rabbit 抗体,靶向 ALDH7A1。Anti-ALDH7A1 Antibody-FITC (5P692) 可用于 FCM。

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产品介绍

生物活性
产品描述
Anti-ALDH7A1 Antibody-FITC (5P692) is a FITC-conjugated Rabbit antibody targeting ALDH7A1. Anti-ALDH7A1 Antibody-FITC (5P692) can be used in FCM.
Ig Type
Monoclonal Rabbit IgG
克隆号
5P692
交叉反应
Human
验证活性
Flow cytometric analysis of Human ALDH7A1 expression in HepG2 cells. The cells were treated according to manufacturer’s manual (BD Pharmingen™ Cat. No. 554714), and then stained with FITC Rabbit anti-Human ALDH7A1. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells.
应用
FCM
推荐剂量
10 μl/Test, 0.1 mg/ml
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Human ALDH7A1 (rh ALDH7A1; TMPY-01588; P49419-2; Ser2-Gln511) and conjugated with FITC under optimum conditions, the unreacted FITC was removed.
纯化方式Protein A
性状Liquid
缓冲液PBS solution containing 0.5% BSA and 0.03%ProClin300
研究背景ALDH7A1 (Aldehyde dehydrogenase 7 family, member A1) is a member of subfamily 7 in the aldehyde dehydrogenase family. These enzymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. Mammalian ALDH7A1 is homologous to plant ALDH7B1 which protects against various forms of stress such as increased salinity, dehydration and treatment with oxidants or pesticides. In mammals, ALDH7A1 is known to play a primary role during lysine catabolism through the NAD+-dependent oxidative conversion of aminoadipate semialdehyde (AASA) to its corresponding carboxylic acid, α-aminoadipic acid. Deleterious mutations in human ALDH7A1 are responsible for pyridoxine-dependent and folinic acid-responsive seizures. ALDH7A1 is a novel aldehyde dehydrogenase expressed in multiple subcellular compartments that protects against hyperosmotic stress by generating osmolytes and metabolizing toxic aldehydes.
偶联与修饰
偶联
FITC
其他可选修饰符
Unconjugated
可提供抗体种类
2
抗原信息
免疫原
Recombinant Human ALDH7A1 protein (TMPY-01588)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal.
运输方式Shipping with blue ice.

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