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Anti-Phospho-H2AFX (Ser139) Antibody (2B111)

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Anti-Phospho-H2AFX (Ser139) Antibody (2B111)
产品编号 TMAC-03223
别名 p-H2AFX (Ser139), p-H2AFX (S139), H2AFX (p-Ser139), H2AFX (p-S139)

Anti-Phospho-H2AFX (S139) Antibody (2B111) 是一种 Rabbit 抗体,靶向 Phospho-H2AFX (S139)。Anti-Phospho-H2AFX (S139) Antibody (2B111) 可用于 WB,IHC,ICC/IF,IP。

Anti-Phospho-H2AFX (Ser139) Antibody (2B111)

Anti-Phospho-H2AFX (Ser139) Antibody (2B111)

Rating icon 还可以
Anti-Phospho-H2AFX (Ser139) Antibody (2B111)
产品编号 TMAC-03223 别名 p-H2AFX (Ser139), p-H2AFX (S139), H2AFX (p-Ser139), H2AFX (p-S139)

Anti-Phospho-H2AFX (S139) Antibody (2B111) 是一种 Rabbit 抗体,靶向 Phospho-H2AFX (S139)。Anti-Phospho-H2AFX (S139) Antibody (2B111) 可用于 WB,IHC,ICC/IF,IP。

规格价格库存数量
50 μL
¥ 1,490
5日内发货
100 μL
¥ 2,495
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-H2AFX (Ser139) Antibody (2B111) 是一种 Rabbit 抗体,靶向 Phospho-H2AFX (Ser139)。Anti-Phospho-H2AFX (Ser139) Antibody (2B111) 可用于 WB,IHC,ICC/IF,IP。
别名p-H2AFX (Ser139), p-H2AFX (S139), H2AFX (p-Ser139), H2AFX (p-S139)
Ig Type
IgG
交叉反应
Human,Mouse,Rat
验证活性
1. Western blot analysis of Phospho-Histone H2A.X (S139) on HepG2 cell lysates using anti-Phospho-Histone H2A.X (S139) antibody at 1/1,000 dilution. Positive control: Lane 1: HepG2 cell lysate treated with etoposide, Lane 2: HepG2 cell lysate untreated.
2. Immunohistochemical analysis of paraffin-embedded mouse testis tissue using anti- Phospho-Histone H2A.X (S139) antibody. Counter stained with hematoxylin.
应用
推荐剂量
WB: 1:1000-5000; IHC: 1:100-200; ICC/IF: 1:50-200; IP: 1:20-50
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景Histone H2A.X is a member of the Histone H2A family, which is involved in nucleosomal organization of chromatin. The H2AFX gene is located in close proximity to the Porphobilinogen deaminase (PBG-D) gene in both mouse and human, and maps to chromosome 9 and 11q23, respectively. H2A.X differs from the other members of the H2A family by the presence of a highly conserved C-terminal motif. It is rapidly phosphorylated in response to ionizing radiation and plays an important role in the recognition and repair of DNA double stranded breaks. The phosphorylated form of H2A.X, designated ?-H2A.X, forms nuclear foci at the heavy chain constant region of cells involved in class switch recombination (CSR), a region-specific DNA reaction that replaces one immunoglobulin heavy chain constant region gene with another. The phosphorylated ?-H2A.X is also thought to initiate subsequent repair factors, including Rad50, Rad51 and BRCA1.
偶联与修饰
偶联
Unconjugated
其他可选修饰符
Phospho
抗原信息
免疫原
A synthesized phosphopeptide: human Histone H2A.X around the phosphorylation site of Ser139
抗原种属
human
Uniprot ID
化学信息
分子量Theoretical: 15 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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