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CBR1 Protein, Human, Recombinant (His)

CBR1 Protein, Human, Recombinant (His)

产品编号 TMPH-01040
别名: 20-beta-hydroxysteroid dehydrogenase, Carbonyl reductase [NADPH] 1, NADPH-dependent carbonyl reductase 1, CBR1, PG-9-KR, 15-hydroxyprostaglandin dehydrogenase [NADP(+)], CBR, Alcohol dehydrogenase [NAD(P)+] CBR1, SDR21C1, CRN, Prostaglandin 9-ketoreductase

CBR1 Protein, Human, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 32.2 kDa and the accession number is P16152.

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CBR1 Protein, Human, Recombinant (His)
规格 价格/CNY 货期 数量
20 μg ¥ 1,470 20日内发货
100 μg ¥ 2,780 20日内发货
500 μg ¥ 7,700 20日内发货
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产品目录号及名称: CBR1 Protein, Human, Recombinant (His) (TMPH-01040)
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产品描述 CBR1 Protein, Human, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 32.2 kDa and the accession number is P16152.
种属 Human
表达系统 P. pastoris (Yeast)
标签 N-6xHis
蛋白编号 P16152
别名 20-beta-hydroxysteroid dehydrogenase, Carbonyl reductase [NADPH] 1, NADPH-dependent carbonyl reductase 1, CBR1, PG-9-KR, 15-hydroxyprostaglandin dehydrogenase [NADP(+)], CBR, Alcohol dehydrogenase [NAD(P)+] CBR1, SDR21C1, CRN, Prostaglandin 9-ketoreductase
氨基酸序列 SSGIHVALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQAEGLSPRFHQLDIDDLQSIRALRDFLRKEYGGLDVLVNNAGIAFKVADPTPFHIQAEVTMKTNFFGTRDVCTELLPLIKPQGRVVNVSSIMSVRALKSCSPELQQKFRSETITEEELVGLMNKFVEDTKKGVHQKEGWPSSAYGVTKIGVTVLSRIHARKLSEQRKGDKILLNACCPGWVRTDMAGPKATKSPEEGAETPVYLALLPPDAEGPHGQFVSEKRVEQW
蛋白构建 2-277 aa
蛋白纯度 > 90% as determined by SDS-PAGE.
分子量 32.2 kDa (predicted)
缓冲液 Tris-based buffer, 50% glycerol
复溶方法 A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储

Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted protein solutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.

研究背景 NADPH-dependent reductase with broad substrate specificity. Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various xenobiotics. Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol. Can convert prostaglandin E to prostaglandin F2-alpha. Can bind glutathione, which explains its higher affinity for glutathione-conjugated substrates. Catalyzes the reduction of S-nitrosoglutathione.

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Keywords

CBR1 Protein, Human, Recombinant (His) 20-beta-hydroxysteroid dehydrogenase Carbonyl reductase [NADPH] 1 NADPH-dependent carbonyl reductase 1 CBR1 PG-9-KR 15-hydroxyprostaglandin dehydrogenase [NADP(+)] CBR Alcohol dehydrogenase [NAD(P)+] CBR1 SDR21C1 CRN Prostaglandin 9-ketoreductase recombinant recombinant-proteins proteins protein

 

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