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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Notch3 Polyclonal Antibody

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货号 TMAB-09572

Anti-Notch3 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Notch3。Anti-Notch3 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF,FCM。

Anti-Notch3 Polyclonal Antibody

Anti-Notch3 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-09572

Anti-Notch3 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Notch3。Anti-Notch3 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF,FCM。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-Notch3 Polyclonal Antibody is a Rabbit antibody targeting Notch3. Anti-Notch3 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF,FCM.
Ig Type
IgG
反应种属
Human,Mouse,Rat
应用IHC-PIHC-FrIFFCM
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; FCM: 1μg/Test
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell membrane; Single-pass type I membrane protein. Notch 3 intracellular domain: Nucleus. Note=Following proteolytical processing NICD is translocated to the nucleus.
组织特异性Ubiquitously expressed in fetal and adult tissues.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景This gene encodes the third discovered human homologue of the Drosophilia melanogaster type I membrane protein notch. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signalling pathway that plays a key role in neural development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remains to be determined. Mutations in NOTCH3 have been identified as the underlying cause of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL). [provided by RefSeq, Jul 2008]
抗原信息
免疫原
KLH conjugated synthetic peptide: mouse Notch3
抗原种属
Mouse
基因名称
NOTCH3
基因ID
18131
蛋白名称
Neurogenic locus notch homolog protein 3
Uniprot ID
Q61982
功能
Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs.
化学信息
分子量Theoretical: 255 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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