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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-CD130 Polyclonal Antibody

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货号 TMAB-03837

Anti-CD130 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 CD130。Anti-CD130 Polyclonal Antibody 可用于 WB,ELISA,ICC/IF。

Anti-CD130 Polyclonal Antibody

Anti-CD130 Polyclonal Antibody

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货号 TMAB-03837

Anti-CD130 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 CD130。Anti-CD130 Polyclonal Antibody 可用于 WB,ELISA,ICC/IF。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,960
5日内发货
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产品介绍

生物活性
产品描述
Anti-CD130 Polyclonal Antibody is a Rabbit antibody targeting CD130. Anti-CD130 Polyclonal Antibody can be used in WB,ELISA,ICC/IF.
Ig Type
IgG
反应种属
Human,Mouse,Rat
应用WBELISAICC/IF
推荐剂量
WB: 1:500-2000; ELISA: 1:5000-10000; ICC/IF: 1:50 - 1:200
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Isoform 1: Cell membrane; Single-pass type I membrane protein. Isoform 2: Secreted.
组织特异性Found in all the tissues and cell lines examined. Expression not restricted to IL6 responsive cells.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景bs-1459P is one synthetic peptide derived from human IL6R beta. CD130 is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggested a critical role of the gene encoding this protein in regulating myocyte apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been described.
抗原信息
免疫原
Recombinant Protein: human CD130 protein
抗原种属
Human
基因名称
IL6ST
基因ID
3572
蛋白名称
Interleukin-6 receptor subunit beta
Uniprot ID
P40189
功能
Signal-transducing molecule. The receptor systems for IL6, LIF, OSM, CNTF, IL11, CTF1 and BSF3 can utilize gp130 for initiating signal transmission. Binds to IL6/IL6R (alpha chain) complex, resulting in the formation of high-affinity IL6 binding sites, and transduces the signal. Does not bind IL6. May have a role in embryonic development. The type I OSM receptor is capable of transducing OSM-specific signaling events.
化学信息
分子量Theoretical: 103 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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