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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-DVL1 Polyclonal Antibody

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货号 TMAB-05357

Anti-DVL1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 DVL1。Anti-DVL1 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-DVL1 Polyclonal Antibody

Anti-DVL1 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-05357

Anti-DVL1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 DVL1。Anti-DVL1 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-DVL1 Polyclonal Antibody is a Rabbit antibody targeting DVL1. Anti-DVL1 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human,Mouse,Rat
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell membrane. Cytoplasm, cytosol. Cytoplasmic vesicle. Localizes at the cell membrane upon interaction with frizzled family members.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景DVL1 may play a role in the signal transduction pathway mediated by multiple Wnt genes. [Subunit] Interacts with BRD7 and INVS. Interacts through its PDZ domain with the C-terminal regions of VANGL1, VANGL2 and CCDC88C/DAPLE. Interacts (via PDZ domain) with NXN (By similarity). Interacts with CXXC4. [Subcellular Location] Cytoplasm (Potential). Belongs to the DSH family.
抗原信息
免疫原
KLH conjugated synthetic peptide: human DVL1
抗原种属
Human
基因名称
DVL1
基因ID
1855
蛋白名称
Segment polarity protein dishevelled homolog DVL-1
Uniprot ID
O14640
功能
Participates in Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors. Plays a role both in canonical and non-canonical Wnt signaling. Plays a role in the signal transduction pathways mediated by multiple Wnt genes. Required for LEF1 activation upon WNT1 and WNT3A signaling. DVL1 and PAK1 form a ternary complex with MUSK which is important for MUSK-dependent regulation of AChR clustering during the formation of the neuromuscular junction (NMJ).
化学信息
分子量Theoretical: 76 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

  • 稀释 计算器
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