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别名 RNS4I, RNS 4I, RNASELI, RNASEL1, RNase L Inhibitor, RLI, Ribonuclease L(2'5' oligoisoadenylate synthetase dependent) inhibitor, Ribonuclease L(2' 5' oligoisoadenylate synthetase dependent) inhibitor, Ribonuclease L inhibitor, Ribonuclease 4 Inhibitor, OABP, HuHP68, HuHP 68, ATP-binding cassette sub-family E member 1, ATP binding cassette sub family E(OABP) member 1, ATP binding cassette sub family E member 1, ABCE1_HUMAN, ABCE1, ABCE 1, ABC38, ABC 38, 2''-5''-oligoadenylate-binding protein, 2'5' oligoadenylate binding protein, 2' 5' oligoadenylate binding protein
Anti-ABCE1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 ABCE1。Anti-ABCE1 Polyclonal Antibody 可用于 WB。
Anti-ABCE1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 ABCE1。Anti-ABCE1 Polyclonal Antibody 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,175 | 5日内发货 | |
| 100 μL | ¥ 1,975 | 5日内发货 | |
| 200 μL | ¥ 2,790 | 5日内发货 |
| 产品描述 | Anti-ABCE1 Polyclonal Antibody is a Rabbit antibody targeting ABCE1. Anti-ABCE1 Polyclonal Antibody can be used in WB. |
| 别名 | RNS4I, RNS 4I, RNASELI, RNASEL1, RNase L Inhibitor, RLI, Ribonuclease L(2'5' oligoisoadenylate synthetase dependent) inhibitor, Ribonuclease L(2' 5' oligoisoadenylate synthetase dependent) inhibitor, Ribonuclease L inhibitor, Ribonuclease 4 Inhibitor, OABP, HuHP68, HuHP 68, ATP-binding cassette sub-family E member 1, ATP binding cassette sub family E(OABP) member 1, ATP binding cassette sub family E member 1, ABCE1_HUMAN, ABCE1, ABCE 1, ABC38, ABC 38, 2''-5''-oligoadenylate-binding protein, 2'5' oligoadenylate binding protein, 2' 5' oligoadenylate binding protein |
| Ig Type | IgG |
| 反应种属 | Rat (predicted:Human,Mouse,Chicken,Cow,Horse) |
| 验证活性 | Sample: Brain (Rat) Lysate at 40 μg Liver (Rat) Lysate at 40 μg Primary: Anti-ABCE1 (TMAB-02156) at 1/300 dilution Secondary: HRP conjugated Goat-Anti-rabbit IgG at 1/5000 dilution Predicted band size: 67 kD Observed band size: 66 kD |
| 应用 | WB |
| 推荐剂量 | WB: 1:500-2000 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Cytoplasm. Mitochondrion. Note=Localized to clusters of virus formation at the plasma membrane. |
| 构建方式 | Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | ABCE1 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the OABP subfamily. It is alternatively referred to as the RNase L inhibitor as it functions to block the activity of ribonuclease L(referenced from entrez gene). |
| 免疫原 | KLH conjugated synthetic peptide: human ABCE1 |
| 抗原种属 | Human |
| 基因名称 | ABCE1 |
| 基因ID | |
| 蛋白名称 | ATP-binding cassette sub-family E member 1 |
| Uniprot ID | |
| 功能 | Antagonizes the binding of 2-5A (5'-phosphorylated 2',5'-linked oligoadenylates) by RNase L through direct interaction with RNase L and therefore inhibits its endoribonuclease activity. May play a central role in the regulation of mRNA turnover. Antagonizes the anti-viral effect of the interferon-regulated 2-5A/RNase L pathway. May act as a chaperone for post-translational events during HIV-1 capsid assembly. |
| 分子量 | Theoretical: 67 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |