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Anti-IL-13RA2 Antibody (9B615)

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Anti-IL-13RA2 Antibody (9B615)
产品编号 TMAY-00669
别名 interleukin 13 receptor, α2, interleukin 13 receptor, alpha 2, CD213a2

Anti-IL-13RA2 Antibody (9B615) 是一种 Rabbit 抗体,靶向 IL-13RA2。Anti-IL-13RA2 Antibody (9B615) 可用于 FCM。

Anti-IL-13RA2 Antibody (9B615)

Anti-IL-13RA2 Antibody (9B615)

Rating icon 还可以
Anti-IL-13RA2 Antibody (9B615)
产品编号 TMAY-00669 别名 interleukin 13 receptor, α2, interleukin 13 receptor, alpha 2, CD213a2

Anti-IL-13RA2 Antibody (9B615) 是一种 Rabbit 抗体,靶向 IL-13RA2。Anti-IL-13RA2 Antibody (9B615) 可用于 FCM。

规格价格库存数量
100 μL
¥ 2,284
5日内发货
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TargetMol 的所有产品仅用作科学研究或药证申报,不能被用于人体,我们不向个人提供产品和服务。请您遵守承诺用途,不得违反法律法规规定用于任何其他用途。
实验操作小课堂
常见问题解答
化合物带有盐酸盐离子、硫酸盐离子等是否和其本身有什么区别?盐形式和游离态有什么区别?
盐和非盐形式化合物的活性分子是一样的,在生物实验中起到的效果也一致,活性和使用方法都是一样的。只是由于呈盐不同,物理性质比如溶解度会有差异。建议您根据溶解、实验需求进行选择。
如何选择某个靶点的特异性或总的抑制剂?特异性和非特异性的区别是什么?
抑制剂按照特异性分为广谱 pan 和特异性 selective 两种。Pan 为某个靶点总的抑制剂,对所有亚型或整个家族的成员都有抑制作用。Selective 抑制剂针对某个蛋白激酶的某个亚型或家族中某个成员抑制率特别高或有特异性抑制作用。 一般评价一个抑制剂的抑制效率主要看 IC50 值,IC50 值越低,说明抑制剂效率越高。建议您根据以上几个特征进行综合选择,也可联系技术帮您推荐相关抑制剂。
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产品介绍

生物活性
产品描述
Anti-IL-13RA2 Antibody (9B615) is a Rabbit antibody targeting IL-13RA2. Anti-IL-13RA2 Antibody (9B615) can be used in FCM.
别名interleukin 13 receptor, α2, interleukin 13 receptor, alpha 2, CD213a2
Ig Type
Rabbit IgG
克隆号
9B615
交叉反应
Human
验证活性
Flow cytometric analysis of Human IL13Ra2(CD213a2) expression on A375 cells. Cells were stained with purified anti-Human IL13Ra2(CD213a2), then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells.
应用
FCM
推荐剂量
FCM: 1:25-1:100
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Human IL13RA2 / CD213A2 (rh IL13RA2 / CD213A2; TMPY-00841; NP_000631.1; Met1-Leu342).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Interleukin-13 receptor subunit alpha-2 (IL13RA2/IL-13RA2) is also known as cluster of differentiation 213A2 (CD213A2), IL-13 receptor subunit alpha-2, IL-13R subunit alpha-2, and IL-13RA2. The IL13RA2 is often overexpressed in brain tumors, making Il13ra2 one of the vaccine targets for immunotherapy of glioma. IL13RA2/IL-13RA2 is a cancer-associated receptor that is present in greater than 80% of High-Grade Astrocytomas (HGA) and has recently been recognized as a cytokine that predisposes breast cancer cells to metastasize. Expression of IL13Rα2 was rapidly lost from the surface of transduced cells grown in culture. The loss appeared to be related to ligands present in fetal bovine serum in the medium. None of the malignant glioma cell lines cultivated in vitro and tested to date exhibited the IL13Rα2 receptor. A recombinant virus (R5111) enters cells via its interaction with the IL13Rα2 receptor in a manner that cannot be differentiated from the interaction of wild-type virus with its receptors.
偶联与修饰
偶联
Unconjugated
其他可选修饰符
APC/FITC/PE
可提供抗体种类
4
抗原信息
免疫原
Recombinant Protein: Human IL13RA2 / CD213A2 Protein (TMPY-00841)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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