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Anti-Nectin-2 Antibody (1B632) 是一种 Mouse 抗体,靶向 Nectin-2。Anti-Nectin-2 Antibody (1B632) 可用于 ELISA。
Anti-Nectin-2 Antibody (1B632) 是一种 Mouse 抗体,靶向 Nectin-2。Anti-Nectin-2 Antibody (1B632) 可用于 ELISA。
产品描述 | Anti-Nectin-2 Antibody (1B632) is a Mouse antibody targeting Nectin-2. Anti-Nectin-2 Antibody (1B632) can be used in ELISA. |
Ig Type | Monoclonal Mouse IgG1 |
克隆号 | 1B632 |
交叉反应 | Human |
应用 | ELISA |
推荐剂量 | ELISA: 1:1000-1:2000 |
抗体种类 | Monoclonal |
宿主来源 | Mouse |
构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD112 / Nectin2 extracellular domain (rhCD112; TMPY-00747; Met1-Leu360; NP_002847.1). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | Cluster of Differentiation 112 (CD112), also known as poliovirus receptor related protein 2 (PVRL2 or PRR2), is a single-pass type I transmembrane glycoprotein belonging to the Immunoglobulin superfamily. CD112 protein also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and thus is involved in cell to cell spreading of these viruses. CD112 protein has been identified as the ligand for DNAM-1 (CD226), and the interaction of CD226/CD112 protein can induce NK cell- and CD8+T cell-mediated cytotoxicity and cytokine secretion. CD112 has been regarded as a critical component in allergic reactions, and accordingly may function as a novel target for anti-allergic therapy. |
偶联 | Unconjugated |
免疫原 | Human cell-derived rhCD112 (TMPY-00747) |
抗原种属 | Human |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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