购物车
- 全部删除
您的购物车当前为空
Anti-CREB1 Antibody (5G910)
还可以产品编号 TMAY-00222
Anti-CREB1 Antibody (5G910) 是一种 Mouse 抗体，靶向 CREB1。Anti-CREB1 Antibody (5G910) 可用于 FCM,ICC/IF。
Anti-CREB1 Antibody (5G910)
Anti-CREB1 Antibody (5G910)
还可以产品编号 TMAY-00222
Anti-CREB1 Antibody (5G910) 是一种 Mouse 抗体，靶向 CREB1。Anti-CREB1 Antibody (5G910) 可用于 FCM,ICC/IF。
产品信息正在更新中，如果您想购买，请点击大包装&定制按钮.
大包装 & 定制
联系我们获取更多批次信息
资源下载
产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-CREB1 Antibody (5G910) is a Mouse antibody targeting CREB1. Anti-CREB1 Antibody (5G910) can be used in FCM,ICC/IF. |
| Ig Type | Monoclonal Mouse IgG2b |
| 克隆号 | 5G910 |
| 交叉反应 | Human |
| 验证活性 | 1. Immunofluorescence staining of Human CREB1 in Hela cells. Cells were fixed with 4% PFA, permeabilzed with 0.3% Triton X-100 in PBS, blocked with 10% serum, and incubated with Mouse anti-Human CREB1 monoclonal antibody (1:60) at 37°C 1 hour. Then cells were stained with the Alexa Fluor® 488-conjugated Goat Anti-mouse IgG secondary antibody (green) and counterstained with DAPI (blue). Positive staining was localized to nucleus. 2. Flow cytometric analysis of Human CREB1 expression on HepG2 cells. The cells were treated according to manufacturer’s manual (BD Pharmingen™ Cat. No. 554714), stained with purified anti-Human CREB1, then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
| 应用 | FCM,ICC/IF |
| 推荐剂量 | ICC-IF: 1:20-1:100; FCM: 1:25-1:100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This product is a recombinant monoclonal antibody expressed from HEK293 cells. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | CAMP responsive element binding protein 1, also known as CREB-1, plays multiple functions as a transcription factor in gene regulation. This protein is a CREB transcription factor that is a member of the leucine zipper family of DNA-binding proteins. CREB1 proteins are also known to be expressed in several spliced isoforms that act as transcriptional activators or repressors. The activator isoforms, possessing the functional domains for kinase induction and for interaction with other transcriptional regulators, act as transcriptional activators.The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. CREB-1 has a complex influence on behavioural responses to drugs of abuse which varies depending on the brain region in which it is expressed. CREB-1 is important for serotonin (5-HT)-induced long-term facilitation (LTF) of the sensorimotor synapse in Aplysia. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human CREB1 Protein |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
SCI 文献
计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
评论列表
预览
Related Tags: buy Anti-CREB1 Antibody (5G910) | purchase Anti-CREB1 Antibody (5G910) | Anti-CREB1 Antibody (5G910) cost | order Anti-CREB1 Antibody (5G910)
嗨！有任何问题？点我咨询
评论内容