2-Ethoxybenzamide

Name: 2-Ethoxybenzamide
Brand: TargetMol
SKU: T0058
Price: 197 CNY
Availability: InStock
Rating: 5 (10 reviews)

一键复制产品信息

很棒

纯度: 99.75%

货号 T0058Cas号 938-73-8

别名 止痛灵, Ethenzamide, Anovigam, 2-乙氧基苯甲酰胺

2-Ethoxybenzamide (Anovigam) 常作为解热镇痛药。

2-Ethoxybenzamide

一键复制产品信息

很棒

纯度: 99.75%

货号 T0058 别名 止痛灵, Ethenzamide, Anovigam, 2-乙氧基苯甲酰胺Cas号 938-73-8

2-Ethoxybenzamide (Anovigam) 常作为解热镇痛药。

规格	价格	库存
500 mg	¥ 197	现货
1 g	¥ 247	现货
1 mL x 10 mM (in DMSO)	¥ 247	现货

库存状态实时更新，以官网显示为准，现货产品可直接加购物车下单

大包装 & 定制

加入购物车

TargetMol的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。

实验操作小课堂

常见问题解答

选择批次:

纯度: 99.75%

联系我们获取更多批次信息

资源下载:

COA HPLC HNMR LCMS 产品操作手册

产品介绍

2-Ethoxybenzamide AI Summary

2-Ethoxybenzamide exhibits a range of bioactivities, demonstrating its potential in multiple biological contexts. It shows potency in inhibiting anthrax lethal toxin internalization and acts as an antagonist of androgen receptor signaling. Additionally, it demonstrates agonistic activity towards thyroid hormone receptor beta signaling and displays inhibitory effects on TDP-43. It is effective in blocking the entry of Ebola virus, albeit with varying potencies across different screening channels. In antiviral studies, 2-Ethoxybenzamide shows low bioactivity in inhibiting cell viability in Vero E6 cells infected with SARS-CoV-2 (strain BavPat1). It inhibits SARS-CoV-2-induced cytotoxicity in Caco-2 cells with an inhibition rate of -27.23% at 10 μM concentration after 48 hours. Similarly, it demonstrates antiviral activity in HRCE cells against the SARS-CoV-2 (USA-WA1/2020 strain), with a hit score of 0.115. It also displays varying degrees of inhibitory effects against SARS-CoV-2-induced cytotoxicity in VERO-6 cells, with inhibitory percentages ranging from 0.02% to 0.05% at 10 μM after 48 hours. The IC50 for its antiviral activity is greater than 20,000 nM. Moreover, 2-Ethoxybenzamide exhibits inhibitory activity against the human HDAC6 enzyme, showing 18.68% inhibition using a commercial peptide substrate and 5.47% inhibition using a custom peptide substrate. However, it does not show significant binding affinity or inhibition towards tested receptors and enzymes at higher concentrations (AC50 > 30,000 nM), nor does it demonstrate significant agonistic or antagonistic activities in cell-based assays. Finally, the compound has a low in-vivo plasma to lung partition coefficient in rats, with a logP(lung) value of -0.03, suggesting it may preferentially distribute from the plasma into the lung tissue. Overall, 2-Ethoxybenzamide exhibits multiple bioactivities, indicating a broad spectrum of biological potential, although with variable efficacy across different targets and assays.

Note: Summary generated by AI. Data source: ChEMBL

生物活性

产品描述	2-Ethoxybenzamide (Anovigam) is white or almost-white crystalline powder. Almost odorless. Tasteless. It is widely used as an antipyretic anodyne.
别名	止痛灵, Ethenzamide, Anovigam, 2-乙氧基苯甲酰胺

化学信息

分子量	165.19
分子式	C₉H₁₁NO₂
CAS No.	938-73-8
Smiles	CCOC1=CC=CC=C1C(N)=O
密度	1.111 g/cm3
颜色	White
物理性状	Solid

储存&溶解度

存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

溶解度信息

DMSO: 65 mg/mL (393.49 mM), Sonication is recommended.

溶液配制表

DMSO

	1mg	5mg	10mg	50mg
1 mM	6.0536 mL	30.2682 mL	60.5364 mL	302.6818 mL
5 mM	1.2107 mL	6.0536 mL	12.1073 mL	60.5364 mL
10 mM	0.6054 mL	3.0268 mL	6.0536 mL	30.2682 mL
20 mM	0.3027 mL	1.5134 mL	3.0268 mL	15.1341 mL
50 mM	0.1211 mL	0.6054 mL	1.2107 mL	6.0536 mL
100 mM	0.0605 mL	0.3027 mL	0.6054 mL	3.0268 mL