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Oseltamivir phosphate (GS 4104) 是一种神经氨酸酶 (NA) 抑制剂,具有口服活性。Oseltamivir phosphate 具有抗病毒活性,对多种流感病毒有效,可以抑制成熟的流感病毒脱离宿主细胞。

Oseltamivir phosphate (GS 4104) 是一种神经氨酸酶 (NA) 抑制剂,具有口服活性。Oseltamivir phosphate 具有抗病毒活性,对多种流感病毒有效,可以抑制成熟的流感病毒脱离宿主细胞。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 mg | ¥ 196 | In stock | |
| 100 mg | ¥ 316 | In stock | |
| 200 mg | ¥ 497 | In stock | |
| 1 mL x 10 mM (in DMSO) | ¥ 190 | In stock |
Oseltamivir phosphate 相关产品
| 产品描述 | Oseltamivir phosphate (GS 4104) is a neuraminidase (NA) inhibitor with oral activity. Oseltamivir phosphate has antiviral activity and is effective against a wide range of influenza viruses, inhibiting mature influenza viruses from breaking away from host cells. |
| 靶点活性 | A/H3N2 virus:0.42 ± 0.29 µM (EC50), MDCK cells:1.1 μM |
| 体外活性 | 方法:MDCK 细胞用 Oseltamivir phosphate (100 µM) 处理 1 h,再用各种人类甲型流感病毒株感染,收集上清液,通过 TCID50 assay 测定上清液中的病毒滴度。 |
| 体内活性 | 方法:为研究体内抗流感病毒活性,将 Oseltamivir phosphate (10 mg/kg) 灌胃给致死性 A/PR/8/34 (H1N1) 病毒感染的 C57BL/6 小鼠,每天一次,持续 5 天。 |
| 细胞实验 | Cells are incubated in 96-well plates (5,000 cells/well) and allowed to adhere for 24 hours in 1× DMEM media containing 10% FCS. The media are replaced with fresh DMEM media containing 5% FCS with or without various concentrations of tamoxifen or OP for indicated time periods. Cell viability is tested using WST-1 cell proliferation assay.(Only for Reference) |
| 别名 | 磷酸奥司他韦, GS 4104 |
| 分子量 | 410.4 |
| 分子式 | C16H28N2O4·H3PO4 |
| CAS No. | 204255-11-8 |
| Smiles | [C@H]1([C@H]([C@@H](C=C(C1)C(=O)OCC)OC(CC)CC)NC(=O)C)N.P(=O)(O)(O)O |
| 密度 | 1.08g/cm3 |
| 颜色 | White |
| 物理性状 | Solid |
| 存储 | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||||||||||||
| 溶解度信息 | DMSO: 242.5 mg/mL (590.89 mM), Sonication is recommended. H2O: 80 mg/mL (194.93 mM), Sonification is recommended. | |||||||||||||||||||||||||||||||||||
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