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Anti-HNRNPK Antibody (5Q710)

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Anti-HNRNPK Antibody (5Q710)
产品编号 TMAC-01997
别名 TUNP, Transformation upregulated nuclear protein, Transformation up regulated nuclear protein, HNRNPK, hnRNP K, Heterogeneous nuclear ribonucleoprotein K, FLJ41122, dC stretch binding protein, CSBP

Anti-HNRNPK Antibody (5Q710) 是一种 Rabbit 抗体,靶向 HNRNPK。Anti-HNRNPK Antibody (5Q710) 可用于 WB,ICC/IF,IHC,IP。

Anti-HNRNPK Antibody (5Q710)

Anti-HNRNPK Antibody (5Q710)

Rating icon 还可以
Anti-HNRNPK Antibody (5Q710)
产品编号 TMAC-01997 别名 TUNP, Transformation upregulated nuclear protein, Transformation up regulated nuclear protein, HNRNPK, hnRNP K, Heterogeneous nuclear ribonucleoprotein K, FLJ41122, dC stretch binding protein, CSBP

Anti-HNRNPK Antibody (5Q710) 是一种 Rabbit 抗体,靶向 HNRNPK。Anti-HNRNPK Antibody (5Q710) 可用于 WB,ICC/IF,IHC,IP。

规格价格库存数量
50 μL
¥ 1,485
5日内发货
100 μL
¥ 2,490
5日内发货
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产品介绍

生物活性
产品描述
Anti-HNRNPK Antibody (5Q710) is a Rabbit antibody targeting HNRNPK. Anti-HNRNPK Antibody (5Q710) can be used in WB,ICC/IF,IHC,IP.
别名TUNP, Transformation upregulated nuclear protein, Transformation up regulated nuclear protein, HNRNPK, hnRNP K, Heterogeneous nuclear ribonucleoprotein K, FLJ41122, dC stretch binding protein, CSBP
Ig Type
IgG
交叉反应
Human,Mouse,Rat
验证活性
1. Western blot analysis of hnRNP K on different lysates using anti-hnRNP K antibody at 1/1,000 dilution. Positive control: Lane 1: Jurkat, Lane 2: Hela, Lane 3: NIH/3T3.
2. Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using anti-hnRNP K antibody. Counter stained with hematoxylin.
3. Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-hnRNP K antibody. Counter stained with hematoxylin.
4. Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using anti-hnRNP K antibody. Counter stained with hematoxylin.
5. ICC staining hnRNP K in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
6. ICC staining hnRNP K in HepG2 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
7. ICC staining hnRNP K in SKOV-3 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
应用
推荐剂量
WB: 1:1000-5000; IHC: 1:50-200; ICC/IF: 1:50-200
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景Heterogeneous nuclear ribonucleoproteins (hnRNPs) constitute a set of poly-peptides that contribute to mRNA transcription and pre-mRNA processing as well as mature mRNA transport to the cytoplasm and translation. They also bind heterogeneous nuclear RNA (hnRNA), which are the transcripts produced by RNA Polymerase II. There are approximately 20 known hnRNP proteins and their complexes are the major constituents of the spliceosome. The majority of hnRNP protein are localized to the nucleus, however some shuttle between the nucleus and the cytoplasm, such as hnRNP K. hnRNP K recruits a variety of molecular partners through two K homologous (KH) domains, which are required for protein-protein interactions. hnRNP K also contains several potential phosphorylation sites, including Ser 302, the major site of PKCd phosphorylation, which are thought to regulate various cellular functions, including sequence-specific DNA binding, transcription, RNA binding and nucleocytoplasmic shuttling.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
化学信息
分子量Theoretical: 60 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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