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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-ABRAXAS1 Antibody (4Z976)

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货号 TMAB-02178

Anti-ABRAXAS1 Antibody (4Z976) 是一种 Rabbit 抗体，靶向 ABRAXAS1。Anti-ABRAXAS1 Antibody (4Z976) 可用于 WB,ICC/IF,IP,FCM。

Anti-ABRAXAS1 Antibody (4Z976)

Anti-ABRAXAS1 Antibody (4Z976)

一键复制产品信息
Rating icon 还可以
货号 TMAB-02178

Anti-ABRAXAS1 Antibody (4Z976) 是一种 Rabbit 抗体，靶向 ABRAXAS1。Anti-ABRAXAS1 Antibody (4Z976) 可用于 WB,ICC/IF,IP,FCM。

规格价格库存数量
25 μL
¥ 795
5日内发货
50 μL
¥ 1,380
5日内发货
100 μL
¥ 2,480
5日内发货
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产品介绍

生物活性
产品描述
Anti-ABRAXAS1 Antibody (4Z976) is a Rabbit antibody targeting ABRAXAS1. Anti-ABRAXAS1 Antibody (4Z976) can be used in WB,ICC/IF,IP,FCM.
Ig Type
IgG
克隆号
4Z976
反应种属
Human
应用WBICC/IFIPFCM
推荐剂量
WB: 1:1000-2000; ICC/IF: 1:50-200; IP: 1:20-50; FCM: 1:50-100
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Nucleus. Note=Localizes at sites of DNA damage at double-strand breaks (DSBs).
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究背景Involved in DNA damage response and double-strand break (DSB) repair. Component of the BRCA1-A complex, acting as a central scaffold protein that assembles the various components of the complex and mediates the recruitment of BRCA1. The BRCA1-A complex specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesion sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at DSBs.
抗原信息
免疫原
A synthesized peptide: human ABRAXAS1
抗原种属
Human
基因名称
ABRAXAS1
基因ID
84142
蛋白名称
BRCA1-A complex subunit Abraxas 1
Uniprot ID
Q6UWZ7
功能
Component of the BRCA1-A complex, a complex that specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). The BRCA1-A complex also possesses deubiquitinase activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX. In the BRCA1-A complex, it acts as a central scaffold protein that assembles the various components of the BRCA1-A complex and mediates the recruitment of BRCA1.
化学信息
分子量Theoretical: 47 kDa. Actual: 50 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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