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顶部生物活性储存和溶解信息计算器

Anti-EZH2 Antibody (5A657)

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Anti-EZH2 Antibody (5A657)
产品编号 TMAC-02335
别名 Lysine N-methyltransferase 6, KMT6, Histone-lysine N-methyltransferase EZH2, EZH 2, ENX-1, Enhancer of zeste homolog 2, EC 2.1.1.43

Anti-EZH2 Antibody (5A657) 是一种 Rabbit 抗体，靶向 EZH2。Anti-EZH2 Antibody (5A657) 可用于 WB,ICC/IF,IHC。

Anti-EZH2 Antibody (5A657)

Anti-EZH2 Antibody (5A657)

Rating icon 还可以
Anti-EZH2 Antibody (5A657)
产品编号 TMAC-02335 别名 Lysine N-methyltransferase 6, KMT6, Histone-lysine N-methyltransferase EZH2, EZH 2, ENX-1, Enhancer of zeste homolog 2, EC 2.1.1.43

Anti-EZH2 Antibody (5A657) 是一种 Rabbit 抗体，靶向 EZH2。Anti-EZH2 Antibody (5A657) 可用于 WB,ICC/IF,IHC。

规格价格库存数量
50 μL
¥ 1,485
5日内发货
100 μL
¥ 2,480
5日内发货
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产品介绍

生物活性
产品描述
Anti-EZH2 Antibody (5A657) is a Rabbit antibody targeting EZH2. Anti-EZH2 Antibody (5A657) can be used in WB,ICC/IF,IHC.
别名Lysine N-methyltransferase 6, KMT6, Histone-lysine N-methyltransferase EZH2, EZH 2, ENX-1, Enhancer of zeste homolog 2, EC 2.1.1.43
Ig Type
IgG
交叉反应
Human
验证活性
1. Western blot analysis of KMT6/EZH2 on different lysates using anti-KMT6/EZH2 antibody at 1/1,000 dilution. Positive control: Lane 1: 293T, Lane 2: 293.
2. Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using anti-KMT6/EZH2 antibody. Counter stained with hematoxylin.
3. Immunohistochemical analysis of paraffin-embedded human lung cancer tissue using anti-KMT6/EZH2 antibody. Counter stained with hematoxylin.
4. Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using anti-KMT6/EZH2 antibody. Counter stained with hematoxylin.
5. ICC staining KMT6/EZH2 in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
6. ICC staining KMT6/EZH2 in MCF-7 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
7. ICC staining KMT6/EZH2 in HepG2 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
应用
WB
ICC/IF
IHC
推荐剂量
WB: 1:1000-2000; IHC: 1:50-200; ICC/IF: 1:50-200
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景In Drosophila, the Polycomb (PcG) gene family encodes chromatin proteins that are required for the repression of homeotic loci in embryonic development. PcG proteins work in conjunction with the trithorax-group (trxG), which activate homeobox gene expression during embryonic development. ENX-1, a mammalian homolog of the Drosophila gene enhancer of zeste, is a PcG protein that is ubiquitously expressed during early embryogenesis and becomes restricted to the central and peripheral nervous systems and sites of fetal hematopoiesis during later development. In the adult, ENX-1 is restricted to specific sites, including spleen, testis and placenta. The gene encoding human ENX-1 transcribes a 746 amino acid polypeptide which contains a trithorax-like domain and a DNA-binding motif. ENX-1 interacts with the proto-oncogene product Vav and is thought to be involved in the proliferation of normal and malignant hematopoietic cells. By altering the regulation of target genes, ENX-1 may also contribute to certain phenotypes of Down syndrome.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
Q15910
化学信息
分子量Theoretical: 86 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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