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顶部产品介绍偶联与修饰抗原信息化学信息储存和溶解信息计算器

Anti-Tyrosinase/TYR Antibody (5B146)

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货号 TMAC-04175

别名 Tyrosinase, TYR, Tumor rejection antigen AB, SK29-AB, Monophenol monooxygenase, LB24-AB

Anti-Tyrosinase/TYR Antibody (5B146) 是一种 Rabbit 抗体，靶向 Tyrosinase/TYR。Anti-Tyrosinase/TYR Antibody (5B146) 可用于 ICC/IF,IHC,WB。

Anti-Tyrosinase/TYR Antibody (5B146)

Anti-Tyrosinase/TYR Antibody (5B146)

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Rating icon 还可以
货号 TMAC-04175 别名 Tyrosinase, TYR, Tumor rejection antigen AB, SK29-AB, Monophenol monooxygenase, LB24-AB

Anti-Tyrosinase/TYR Antibody (5B146) 是一种 Rabbit 抗体，靶向 Tyrosinase/TYR。Anti-Tyrosinase/TYR Antibody (5B146) 可用于 ICC/IF,IHC,WB。

规格价格库存数量
50 μL
¥ 1,480
5日内发货
100 μL
¥ 2,490
5日内发货
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产品介绍

生物活性
产品描述
Anti-Tyrosinase/TYR Antibody (5B146) is a Rabbit antibody targeting Tyrosinase/TYR. Anti-Tyrosinase/TYR Antibody (5B146) can be used in ICC/IF,IHC,WB.
别名Tyrosinase, TYR, Tumor rejection antigen AB, SK29-AB, Monophenol monooxygenase, LB24-AB
Ig Type
IgG
克隆号
5B146
反应种属
Human
验证活性
1. Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-Tyrosinase antibody. Counter stained with hematoxylin.
2. Immunohistochemical analysis of paraffin-embedded human stomach cancer tissue using anti-Tyrosinase antibody. Counter stained with hematoxylin.
3. ICC staining Tyrosinase in A431 cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
4. ICC staining Tyrosinase in B16F1 cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
5. ICC staining Tyrosinase in MCF-7 cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
verifiedActivityverifiedActivityverifiedActivityverifiedActivityverifiedActivity
应用ICC/IFIHCWB
推荐剂量
WB: 1:500-1000; IHC: 1:50-200; ICC/IF: 1:100-500
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds. Catalyzes the initial and rate limiting step in the cascade of reactions leading to melanin production from tyrosine. In addition to hydroxylating tyrosine to DOPA (3,4-dihydroxyphenylalanine), also catalyzes the oxidation of DOPA to DOPA-quinone, and possibly the oxidation of DHI (5,6-dihydroxyindole) to indole-5,6 quinone. Defects in TYR are the cause of albinism oculocutaneous type 1B (OCA1B) [MIM:606952]; also known as albinism yellow mutant type. An autosomal recessive disorder in which the biosynthesis of melanin pigment is reduced in skin, hair, and eyes. It is characterized by partial lack of tyrosinase activity.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
P14679
化学信息
分子量Theoretical: 80 kDa.
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

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