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顶部产品介绍化学信息储存和溶解信息计算器技术支持

ATG5 Protein, Human, Recombinant

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货号 TMPJ-01329

别名 Autophagy protein 5, ATG5, ASP, Apoptosis-specific protein, APG5-like, APG5L

ATG5 is an E2 ubiquitin ligase which is necessary for autophagy. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity, dramatically highly expressed in apoptotic cells. It is activated by ATG7, conjugates to ATG12 and associates with isolation membrane to form cup-shaped isolation membrane and autophagosome. The conjugate complex detaches from the membrane immediately before or after autophagosome formation is completed. ATG5 plays an important role in the apoptotic process, possibly within the modified cytoskeleton.

ATG5 Protein, Human, Recombinant
其他形式的 “ATG5 Protein, Human, Recombinant”:
Complement C3 Protein, Human, Recombinant (His)
Complement C3 Protein, Mouse, Recombinant (aa 994-1310, His)
(-)-Aspartic acid

ATG5 Protein, Human, Recombinant

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Rating icon 很棒
货号 TMPJ-01329 别名 Autophagy protein 5, ATG5, ASP, Apoptosis-specific protein, APG5-like, APG5L

ATG5 is an E2 ubiquitin ligase which is necessary for autophagy. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity, dramatically highly expressed in apoptotic cells. It is activated by ATG7, conjugates to ATG12 and associates with isolation membrane to form cup-shaped isolation membrane and autophagosome. The conjugate complex detaches from the membrane immediately before or after autophagosome formation is completed. ATG5 plays an important role in the apoptotic process, possibly within the modified cytoskeleton.

规格价格库存数量
5 μg
¥ 492
现货
10 μg
¥ 820
现货
20 μg
¥ 1,290
现货
50 μg
¥ 2,480
现货
100 μg
¥ 3,980
现货
200 μg
¥ 6,420
5日内发货
500 μg
¥ 12,100
5日内发货
1 mg
¥ 17,300
5日内发货
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TargetMol的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。
实验操作小课堂
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选择批次:
纯度: Greater than 90% as determined by reducing SDS-PAGE.
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资源下载:
COA重组蛋白用户指南

产品介绍

生物活性
产品描述
ATG5 is an E2 ubiquitin ligase which is necessary for autophagy. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity, dramatically highly expressed in apoptotic cells. It is activated by ATG7, conjugates to ATG12 and associates with isolation membrane to form cup-shaped isolation membrane and autophagosome. The conjugate complex detaches from the membrane immediately before or after autophagosome formation is completed. ATG5 plays an important role in the apoptotic process, possibly within the modified cytoskeleton.
生物活性
Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
研究背景
ATG5 is an E2 ubiquitin ligase which is necessary for autophagy. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity, dramatically highly expressed in apoptotic cells. It is activated by ATG7, conjugates to ATG12 and associates with isolation membrane to form cup-shaped isolation membrane and autophagosome. The conjugate complex detaches from the membrane immediately before or after autophagosome formation is completed. ATG5 plays an important role in the apoptotic process, possibly within the modified cytoskeleton.
种属
Human
表达系统
E. coli
标签Tag Free
蛋白编号Q9H1Y0
氨基酸序列Met1-Asp275
蛋白构建Met1-Asp275
蛋白纯度
Greater than 90% as determined by reducing SDS-PAGE. (QC verified)
缓冲液Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 0.2M NaCl, 1 mM DTT, 40% Glycerol, pH 8.0.
别名Autophagy protein 5, ATG5, ASP, Apoptosis-specific protein, APG5-like, APG5L
内毒素< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
化学信息
分子量33 KDa (reducing condition)
颜色Transparent
物理性状Solution
储存&溶解度
运输方式In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
存储Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

计算器

  • 复溶 计算器
  • 重组蛋白稀释 计算器
  • 比活力 计算器

剂量转换

对于不同动物的给药剂量换算，您也可以参考 更多

技术支持

请阅读 重组蛋白用户指南 了解更多具体信息.

关键词

ATG-5ATG 5
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