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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-RACGAP1 Antibody (8E200)

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货号 TMAB-12029

Anti-RACGAP1 Antibody (8E200) 是一种 Rabbit 抗体，靶向 RACGAP1。Anti-RACGAP1 Antibody (8E200) 可用于 IHC-P,IHC-Fr,IF。

Anti-RACGAP1 Antibody (8E200)

Anti-RACGAP1 Antibody (8E200)

一键复制产品信息
Rating icon 还可以
货号 TMAB-12029

Anti-RACGAP1 Antibody (8E200) 是一种 Rabbit 抗体，靶向 RACGAP1。Anti-RACGAP1 Antibody (8E200) 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
25 μL
¥ 795
5日内发货
50 μL
¥ 1,390
5日内发货
100 μL
¥ 2,495
5日内发货
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产品介绍

生物活性
产品描述
Anti-RACGAP1 Antibody (8E200) is a Rabbit antibody targeting RACGAP1. Anti-RACGAP1 Antibody (8E200) can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
克隆号
8E200
反应种属
Human
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Nucleus. Cytoplasm. Cytoplasm, cytoskeleton, spindle.
组织特异性Highly expressed in testis, thymus and placenta. Expressed at lower levels in spleen and peripheral blood lymphocytes. In testis, expression is restricted to germ cells with the highest levels of expression found in spermatocytes. Expression is regulated in a cell cycle-dependent manner and peaks during G2/M phase.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究背景Component of the centralspindlin complex that serves as a microtubule-dependent and Rho-mediated signaling required for the myosin contractile ring formation during the cell cycle cytokinesis. Required for proper attachment of the midbody to the cell membrane during cytokinesis. Sequentially binds to ECT2 and RAB11FIP3 which regulates cleavage furrow ingression and abscission during cytokinesis.
抗原信息
免疫原
A synthesized peptide: human RacGAP1
抗原种属
Human
基因名称
RACGAP1
基因ID
29127
蛋白名称
Rac GTPase-activating protein 1
Uniprot ID
Q9H0H5
功能
Component of the centralspindlin complex that serves asa microtubule-dependent and Rho-mediated signaling required for themyosin contractile ring formation during the cell cyclecytokinesis. Plays key roles in controlling cell growth anddifferentiation of hematopoietic cells through mechanisms otherthan regulating Rac GTPase activity. Also involved in theregulation of growth-related processes in adipocytes and myoblasts.May be involved in regulating spermatogenesis and in the RACGAP1pathway in neuronal proliferation. Shows strong GAP (GTPaseactivation) activity towards CDC42 and RAC1 and less towards RHOA.Essential for the early stages of embryogenesis. May play a role inregulating cortical activity through RHOA during cytokinesis. Mayparticipate in the regulation of sulfate transport in male germcells.
化学信息
分子量Theoretical: 71 kDa. Actual: 71 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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