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Anti-PCSK1/NEC1 Polyclonal Antibody

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货号 TMAB-10080

Anti-PCSK1/NEC1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 PCSK1/NEC1。Anti-PCSK1/NEC1 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-PCSK1/NEC1 Polyclonal Antibody

Anti-PCSK1/NEC1 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-10080

Anti-PCSK1/NEC1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 PCSK1/NEC1。Anti-PCSK1/NEC1 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-PCSK1/NEC1 Polyclonal Antibody is a Rabbit antibody targeting PCSK1/NEC1. Anti-PCSK1/NEC1 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human,Mouse (predicted:Rat,Chicken,Pig,Cow,Horse,Rabbit,Sheep)
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasmic vesicle > secretory vesicle. Localized in the secretion granules.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER and sorts to subcellular compartments where a second autocatalytic even takes place and the catalytic activity is acquired. The protease is packaged into and activated in dense core secretory granules and expressed in the neuroendocrine system and brain. This gene encodes one of the seven basic amino acid-specific members which cleave their substrates at single or paired basic residues. It functions in the proteolytic activation of polypeptide hormones and neuropeptides precursors. Mutations in this gene have been associated with susceptibility to obesity and proprotein convertase 1/3 deficiency. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene [provided by RefSeq, Jan 2014]
抗原信息
免疫原
KLH conjugated synthetic peptide: human PCSK1/NEC1
抗原种属
Human
基因名称
PCSK1
基因ID
5122
蛋白名称
Neuroendocrine convertase 1
Uniprot ID
P29120
功能
Involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. Substrates include POMC, renin, enkephalin, dynorphin, somatostatin, insulin and AGRP.
化学信息
分子量Theoretical: 71 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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