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Anti-Phospho-CD31 (Tyr713) Polyclonal Antibody
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产品编号 TMAC-03152
别名 p-CD31 (Y713), p-CD31 (Tyr713), CD31 (p-Y713), CD31 (p-Tyr713)
Anti-Phospho-CD31 (Tyr713) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-CD31 (Tyr713)。Anti-Phospho-CD31 (Tyr713) Polyclonal Antibody 可用于 WB,IHC,IF。
Anti-Phospho-CD31 (Tyr713) Polyclonal Antibody
Anti-Phospho-CD31 (Tyr713) Polyclonal Antibody
还可以产品编号 TMAC-03152 别名 p-CD31 (Y713), p-CD31 (Tyr713), CD31 (p-Y713), CD31 (p-Tyr713)
Anti-Phospho-CD31 (Tyr713) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-CD31 (Tyr713)。Anti-Phospho-CD31 (Tyr713) Polyclonal Antibody 可用于 WB,IHC,IF。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,495 | 5日内发货 | |
| 100 μL | ¥ 2,230 | 5日内发货 |
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| 产品描述 | Anti-Phospho-CD31 (Tyr713) Polyclonal Antibody is a Rabbit antibody targeting Phospho-CD31 (Tyr713). Anti-Phospho-CD31 (Tyr713) Polyclonal Antibody can be used in WB,IHC,IF. |
| 别名 | p-CD31 (Y713), p-CD31 (Tyr713), CD31 (p-Y713), CD31 (p-Tyr713) |
| Ig Type | IgG |
| 交叉反应 | Human,Mouse |
| 验证活性 | 1. Western blot analysis of lysates from HepG2 cells. The lane on the right is blocked with the phospho peptide. 2. Immunofluorescence analysis of HeLa cells. The picture on the right is blocked with the phospho peptide. 3. Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Tris-EDTA, pH9.0 was used for antigen retrieval. 2 Antibody was diluted at 1:200 (4°C overnight ). 3,Secondary antibody was diluted at 1:200 (room temperature, 45min). |
| 应用 | |
| 推荐剂量 | WB: 1:500-2000; IHC: 1:100-300; IF: 1:200-1000 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 构建方式 | Polyclonal Antibody |
| 纯化方式 | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| 性状 | Liquid |
| 缓冲液 | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| 研究背景 | Induces susceptibility to atherosclerosis By similarity. Cell adhesion molecule which is required for leukocyte transendothelial migration (TEM) under most inflammatory conditions. Tyr-690 plays a critical role in TEM and is required for efficient trafficking of PECAM1 to and from the lateral border recycling compartment (LBRC) and is also essential for the LBRC membrane to be targeted around migrating leukocytes. Prevents phagocyte ingestion of closely apposed viable cells by transmitting 'detachment' signals, and changes function on apoptosis, promoting tethering of dying cells to phagocytes (the encounter of a viable cell with a phagocyte via the homophilic interaction of PECAM1 on both cell surfaces leads to the viable cell's active repulsion from the phagocyte. |
| 偶联 | Unconjugated |
| 其他可选修饰符 | Phospho |
| 免疫原 | A synthesized phosphopeptide: human PECAM-1 around the phosphorylation site of Tyr713 |
| 抗原种属 | human |
| Uniprot ID |
| 分子量 | Actual: 150 kDa. |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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