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Ftaxilide

Name: Ftaxilide
Brand: TargetMol
SKU: T0144
Price: 108 CNY
Availability: InStock
Rating: 5 (10 reviews)

Synonyms: 伏保克西里, 安息香酸, Histanorm

货号 T0144Cas号 19368-18-4 一键复制产品信息纯度: 99.89%

很棒

Ftaxilide (Histanorm) 是新型抗结核剂。

Ftaxilide

一键复制产品信息

很棒

纯度: 99.89%

货号 T0144Cas号 19368-18-4

别名 伏保克西里, 安息香酸, Histanorm

Ftaxilide (Histanorm) 是新型抗结核剂。

规格	价格	库存
5 mg	¥ 108	现货
10 mg	¥ 142	现货
25 mg	¥ 213	现货
50 mg	¥ 318	现货
100 mg	¥ 519	现货
500 mg	¥ 1,270	现货
1 mL x 10 mM (in DMSO)	¥ 195	现货

库存状态实时更新，以官网显示为准，现货产品可直接加购物车下单

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TargetMol的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。

实验操作小课堂

常见问题解答

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纯度: 99.89%

颜色: 白色

性状: Solid

资源下载: COA LCMS HPLC HNMR产品操作手册

产品介绍

Ftaxilide AI Summary

Ftaxilide exhibits notable bioactivities as an inhibitor in various assays. It inhibits DNA Polymerase Beta with a potency of 316.2 nM, Polymerase Iota with a potency of 89125.1 nM, and human tyrosyl-DNA phosphodiesterase 1 (TDP1) with a potency of 33498.3 nM. Additionally, it serves as a delayed death inhibitor of the malarial parasite plastid, showing a potency of 92.8 nM after 48-hour incubation and 11689.1 nM after 96-hour incubation. It also inhibits AMA1-RON, a target in antimalarial drug development, with a potency of 4466.8 nM. In antiviral assays against SARS-CoV-2, Ftaxilide demonstrates limited efficacy. It reduces SARS-CoV-2 induced cytotoxicity by 4.15% in Caco-2 cells at 10 µM over 48 hours and by 0.12% in Vero-6 cells at the same concentration and duration. Additionally, it inhibits the SARS-CoV-2 3CL-Pro protease by 6.192% at 20 µM in a FRET-based assay, yet the IC50 value for inhibiting cytotoxicity in Vero-6 cells exceeds 20000.0 nM, reflecting low potency. Regarding enzymatic inhibition, Ftaxilide inhibits the human HDAC6 enzyme, achieving 2.75% inhibition with a commercial peptide substrate and -5.37% inhibition using a custom peptide substrate in respective assays..

Note: Summary generated by AI. Data source: ChEMBL

生物活性

产品描述	Ftaxilide (Histanorm) has antibacterial property, used as antiseptic.
别名	伏保克西里, 安息香酸, Histanorm

化学信息

分子量	269.3
分子式	C₁₆H₁₅NO₃
CAS No.	19368-18-4
Smiles	Cc1cccc(C)c1NC(=O)c1ccccc1C(O)=O
密度	1.262 g/cm3 (Predicted)

储存&溶解度

存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

实际储存温度请以COA为准

溶解度信息

DMSO: 55 mg/mL (204.23 mM), Sonication is recommended.

溶液配制表

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.7133 mL	18.5667 mL	37.1333 mL	185.6665 mL
5 mM	0.7427 mL	3.7133 mL	7.4267 mL	37.1333 mL
10 mM	0.3713 mL	1.8567 mL	3.7133 mL	18.5667 mL
20 mM	0.1857 mL	0.9283 mL	1.8567 mL	9.2833 mL
50 mM	0.0743 mL	0.3713 mL	0.7427 mL	3.7133 mL
100 mM	0.0371 mL	0.1857 mL	0.3713 mL	1.8567 mL

该溶液配制表仅适用于固体产品。对于液体产品，请根据标明的浓度或密度计算稀释方案。

计算器

摩尔浓度计算器
稀释计算器
配液计算器
分子量计算器

体内实验配液计算器

请在以下方框中输入您的动物实验信息后点击计算，可以得到母液配置方法和体内配方的制备方法：

比如您的给药剂量是10 mg/kg，每只动物体重20 g，给药体积100 μL，一共给药动物10只，您使用的配方为 10% DMSO + 40% PEG300 + 5% Tween 80 + 45% Saline / PBS / ddH₂O，那么您的工作液浓度为2 mg/mL。

母液配置方法：2 mg 药物溶于 100 μL DMSO （母液浓度为 20 mg/mL ）, 如您需要配置的浓度超过该产品的溶解度，请先与我们联系。