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Anti-Vitronectin Antibody (8S645) 是一种 Rabbit 抗体,靶向 Vitronectin。Anti-Vitronectin Antibody (8S645) 可用于 ELISA,IHC-P。
Anti-Vitronectin Antibody (8S645) 是一种 Rabbit 抗体,靶向 Vitronectin。Anti-Vitronectin Antibody (8S645) 可用于 ELISA,IHC-P。
产品描述 | Anti-Vitronectin Antibody (8S645) is a Rabbit antibody targeting Vitronectin. Anti-Vitronectin Antibody (8S645) can be used in ELISA,IHC-P. |
Ig Type | Monoclonal Rabbit IgG |
克隆号 | 8S645 |
交叉反应 | Mouse |
验证活性 | Immunochemical staining of mouse VTN in mouse liver with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). |
应用 | ELISA,IHC-P |
推荐剂量 | ELISA: 1:5000-1:10000; IHC-P: 1:100-1:500 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse Vitronectin / VTN (rM Vitronectin / VTN; TMPY-01861; NP_035837.1; Met1-Lys478). |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | Vitronectin, also known as VTN, is a member of the pexin family. It is an abundant glycoprotein found in serum the extracellular matrix and promotes cell adhesion and spreading. Vitronectin is a secreted protein and exists in either a single chain form or a cleaved, two chain form held together by a disulfide bond. Vitronectin is a plasma glycoprotein implicated as a regulator of diverse physiological process, including blood coagulation, fibrinolysis, pericellular proteolysis, complement dependent immune responses, and cell attachment and spreading. Because of its ability to bind platelet glycoproteins and mediate platelet adhesion and aggregation at sites of vascular injury, vitronectin has become an important mediator in the pathogenesis of coronary atherosclerosis. As a multifunctional protein with a multiple binding domain, Vitronectin interacts with a variety of plasma and cell proteins. Vitronectin binds multiple ligands, including the soluble vitronectin receptor. It may be an independent predictor of adverse cardiovascular outcomes following acute stenting. Accordingly, Vitronectin is suggested to be involved in hemostasis, cell migration, as well as tumor malignancy. |
偶联 | Unconjugated |
免疫原 | Recombinant Mouse Vitronectin / VTN protein (TMPY-01861) |
抗原种属 | Mouse |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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