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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-GCSAM Antibody (3D490)

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货号 TMAB-06399

Anti-GCSAM Antibody (3D490) 是一种 Rabbit 抗体，靶向 GCSAM。Anti-GCSAM Antibody (3D490) 可用于 IHC-P,IHC-Fr,ICC/IF,IF,FCM,WB。

Anti-GCSAM Antibody (3D490)

Anti-GCSAM Antibody (3D490)

一键复制产品信息
Rating icon 还可以
货号 TMAB-06399

Anti-GCSAM Antibody (3D490) 是一种 Rabbit 抗体，靶向 GCSAM。Anti-GCSAM Antibody (3D490) 可用于 IHC-P,IHC-Fr,ICC/IF,IF,FCM,WB。

规格价格库存数量
25 μL
¥ 790
5日内发货
50 μL
¥ 1,380
5日内发货
100 μL
¥ 2,495
5日内发货
库存状态实时更新，以官网显示为准，现货产品可直接加购物车下单
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产品介绍

生物活性
产品描述
Anti-GCSAM Antibody (3D490) is a Rabbit antibody targeting GCSAM. Anti-GCSAM Antibody (3D490) can be used in IHC-P,IHC-Fr,ICC/IF,IF,FCM,WB.
Ig Type
IgG
克隆号
3D490
反应种属
Human
应用IHC-PIHC-FrICC/IFIFFCMWB
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:100-500; IF: 1:100-500; FCM: 1:50-100; WB: 1:500-2000
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Cell membrane. Note=It relocalizes from the cytoplasm to podosome-like structures upon cell treatment with IL6.
组织特异性Expressed in diffuse large B-cell lymphoma (DLBCL) and several germinal center (GC)-like lymphoma cell lines (at protein level). Highly expressed in normal GC lymphocytes and GC-derived malignancies. Expressed in thymus and spleen.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究背景Involved in the negative regulation of lymphocyte motility. It mediates the migration-inhibitory effects of IL6. Serves as a positive regulator of the RhoA signaling pathway. Enhancement of RhoA activation results in inhibition of lymphocyte and lymphoma cell motility by activation of its downstream effector ROCK. Is a regulator of B-cell receptor signaling, that acts through SYK kinase activation.
抗原信息
免疫原
A synthesized peptide: human GCSAM
抗原种属
Human
基因名称
GCSAM
基因ID
257144
蛋白名称
Germinal center-associated signaling and motility protein
Uniprot ID
Q8N6F7
功能
Involved in the negative regulation of lymphocyte motility. It mediates the migration-inhibitory effects of IL6. Serves as a positive regulator of the RhoA signaling pathway. Enhancement of RhoA activation results in inhibition of lymphocyte and lymphoma cell motility by activation of its downstream effector ROCK.
化学信息
分子量Theoretical: 21 kDa. Actual: 21 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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