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顶部生物活性储存和溶解信息计算器

Anti-Phospho-c-Jun (Thr93) Polyclonal Antibody

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产品编号 TMAB-10509

Anti-Phospho-c-Jun (Thr93) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-c-Jun (Thr93)。Anti-Phospho-c-Jun (Thr93) Polyclonal Antibody 可用于 FCM。

Anti-Phospho-c-Jun (Thr93) Polyclonal Antibody

Anti-Phospho-c-Jun (Thr93) Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
产品编号 TMAB-10509

Anti-Phospho-c-Jun (Thr93) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-c-Jun (Thr93)。Anti-Phospho-c-Jun (Thr93) Polyclonal Antibody 可用于 FCM。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-c-Jun (Thr93) Polyclonal Antibody is a Rabbit antibody targeting Phospho-c-Jun (Thr93). Anti-Phospho-c-Jun (Thr93) Polyclonal Antibody can be used in FCM.
Ig Type
IgG
交叉反应
Human (predicted:Mouse,Rat,Chicken,Dog,Pig,Cow,Rabbit,Sheep)
应用FCM
推荐剂量
FCM: 1μg/Test
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景C-jun (Oncoprotein C-jun) is a component of the transcription factor AP-1 that binds and activates transcription at TRE/AP-1 elements and appears to be a major downstream target of the SAPK/JNK signaling pathway. The transcriptional activity of c-Jun is regulated by phosphorylation at Ser63 and Ser73. Extracellular signals including growth factors, transforming oncoproteins and UV irradiation stimulate phosphorylation of c-Jun at Ser63/73 and activate c-Jun dependent transcription. Mutation of Ser63/73 renders c-Jun nonresponsive to mitogenic and stress induced signaling pathways. The MAP kinase homologue, SAPK/JNK, binds to the N-terminal region of c-Jun and phosphorylates c-Jun at Ser63/73. In addition, the activity of SAPK/JNK is stimulated by the same signals that activate c-Jun.
抗原信息
免疫原
KLH conjugated synthesised phosphopeptide: human c-Jun around the phosphorylation site of Thr93
抗原种属
Human
基因名称
JUN
基因ID
3725
蛋白名称
Transcription factor AP-1
Uniprot ID
P05412
功能
Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation.
化学信息
分子量Theoretical: 36 kDa. Actual: 43/36 kDa.
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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