规格

价格

库存

数量

5 μg

¥ 686

5日内发货

10 μg

¥ 1,080

5日内发货

20 μg

¥ 1,690

5日内发货

50 μg

¥ 3,130

5日内发货

100 μg

¥ 4,900

5日内发货

200 μg

¥ 7,970

5日内发货

500 μg

¥ 14,800

5日内发货

生物活性

产品描述	CD58 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 Cells. The accession number is AAH05930.
生物活性	Immobilized Biotinylated Human CD58, His Avi Tag at 1 μg/ml(100 μl/well) on the streptavidin precoated plate (5 μg/ml). Dose response curve for Human CD2, hFc Tag with the EC50 of 3.9 ng/ml determined by ELISA (QC Test).
研究背景	Loss of CD58 is a common mechanism for tumor immune evasion in lymphoid malignancies. CD58 loss is known to occur due to both genetic and non-genetic causes; therefore, we hypothesized that restoring CD58 expression in lymphoma cells may be an effective treatment approach. EZH2 is involved in the epigenetic silencing of CD58 in lymphoma cells as a mechanism for tumor immune escape, and EZH2 inhibitors are able to restore epigenetically suppressed CD58 expression.
种属	Human
表达系统	HEK293 Cells
标签	C-His-Avi
蛋白编号	AAH05930
蛋白构建	Phe29-Arg215
蛋白纯度	> 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC
缓冲液	Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
复溶方法	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
别名	LFA-3, LFA3, LFA 3, CD58 molecule, CD-58, CD58, CD 58, ag3
内毒素	< 1 EU/μg of the protein as determined by the LAL method.

化学信息

分子量	24.37 kDa (Predicted); 35-58 kDa (Reducing condition, due to glycosylation)

储存&溶解度

运输方式

In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.

存储

It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

实际储存温度请以COA为准

CD58 Protein, Human, Recombinant (His & Avi), Biotinylated

CD58 Protein, Human, Recombinant (His & Avi), Biotinylated

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