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Anti-LAMP3/CD208 Antibody (2F47)
还可以产品编号 TMAY-00945
Anti-LAMP3/CD208 Antibody (2F47) 是一种 Mouse 抗体，靶向 LAMP3/CD208。Anti-LAMP3/CD208 Antibody (2F47) 可用于 ELISA。
Anti-LAMP3/CD208 Antibody (2F47)
Anti-LAMP3/CD208 Antibody (2F47)
还可以产品编号 TMAY-00945
Anti-LAMP3/CD208 Antibody (2F47) 是一种 Mouse 抗体，靶向 LAMP3/CD208。Anti-LAMP3/CD208 Antibody (2F47) 可用于 ELISA。
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产品介绍
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偶联与修饰
抗原信息
| 产品描述 | Anti-LAMP3/CD208 Antibody (2F47) is a Mouse antibody targeting LAMP3/CD208. Anti-LAMP3/CD208 Antibody (2F47) can be used in ELISA. |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 2F47 |
| 交叉反应 | Human |
| 应用 | ELISA |
| 推荐剂量 | ELISA: 1:1000-1:2000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD208 / LAMP3 (rh LAMP3; TMPY-01013; NP_055213.2; Lys 28-Thr 381). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Dendritic cell-lysosomal associated membrane protein (DC-LAMP)/CD208, also known as LAMP3, is a member of the lysosomal associated membrane protein (LAMP) family, which is specifically expressed by human dendritic cells (DCs) upon activation and therefore serves as a marker of human DC maturation. Confocal and immunoelectron microscopy showed that mouse DC-LAMP protein co-localizes with lbm180, a specific marker for the limiting membrane of lamellar bodies that contain surfactant protein B. The present study demonstrates that DC-LAMP is constitutively expressed by mouse, sheep, and human type II pneumocytes. DC-LAMP is constitutively expressed in normal type II pneumocytes. DC-LAMP is detected first in the activated human DC within MHC class II molecules-containing compartments just before the translocation of MHC class II-peptide complexes to the cell surface, suggesting a possible involvement in this process. Furthermore, overexpression of LAMP3 is actively involved in tumor invasion through increased migration into lymph-vascular spaces. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human LAMP3 protein (TMPY-01013) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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