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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-PRDM16 Polyclonal Antibody

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货号 TMAB-01571

别名 Transcription factor MEL1, Transcription factor MEL 1, PRD16, PR domain zinc finger protein 16, PR domain containing protein 16, PR domain containing 16, PFM13, PFM 13, MEL1, MDS1/EVI1 like gene 1, LVNC8, KIAA1675, CMD1LL

Anti-PRDM16 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 PRDM16。Anti-PRDM16 Polyclonal Antibody 可用于 ELISA,ICC/IF,IF,IHC-Fr,IHC-P。

Anti-PRDM16 Polyclonal Antibody

Anti-PRDM16 Polyclonal Antibody

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货号 TMAB-01571 别名 Transcription factor MEL1, Transcription factor MEL 1, PRD16, PR domain zinc finger protein 16, PR domain containing protein 16, PR domain containing 16, PFM13, PFM 13, MEL1, MDS1/EVI1 like gene 1, LVNC8, KIAA1675, CMD1LL

Anti-PRDM16 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 PRDM16。Anti-PRDM16 Polyclonal Antibody 可用于 ELISA,ICC/IF,IF,IHC-Fr,IHC-P。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-PRDM16 Polyclonal Antibody is a Rabbit antibody targeting PRDM16. Anti-PRDM16 Polyclonal Antibody can be used in ELISA,ICC/IF,IF,IHC-Fr,IHC-P.
别名Transcription factor MEL1, Transcription factor MEL 1, PRD16, PR domain zinc finger protein 16, PR domain containing protein 16, PR domain containing 16, PFM13, PFM 13, MEL1, MDS1/EVI1 like gene 1, LVNC8, KIAA1675, CMD1LL
Ig Type
IgG
反应种属
(predicted:Human,Mouse,Rat,Cow,Horse,Sheep)
应用ELISAICC/IFIFIHC-FrIHC-P
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:100-500; IF: 1:100-500; ELISA: 1:5000-10000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus.
组织特异性Expressed in uterus and kidney.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1 mg/mL
研究背景The reciprocal translocation t(1;3)(p36;q21) occurs in a subset of myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). This gene is located near the 1p36.3 breakpoint and has been shown to be specifically expressed in the t(1:3)(p36,q21)-positive MDS/AML. The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal PR domain. The translocation results in the overexpression of a truncated version of this protein that lacks the PR domain, which may play an important role in the pathogenesis of MDS and AML. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
抗原信息
免疫原
KLH conjugated synthetic peptide: human PRDM16
抗原种属
Human
基因名称
PRDM16
基因ID
63976
蛋白名称
Histone-lysine N-methyltransferase PRDM16
Uniprot ID
Q9HAZ2
研究领域
Methylation,Zinc Finger
功能
Binds DNA and functions as a transcriptional regulator. Functions in the differentiation of brown adipose tissue (BAT) which is specialized in dissipating chemical energy in the form of heat in response to cold or excess feeding while white adipose tissue (WAT) is specialized in the storage of excess energy and the control of systemic metabolism. Together with CEBPB, regulates the differentiation of myoblastic precursors into brown adipose cells. Functions also as a repressor of TGF-beta signaling. Isoform 4 may regulate granulocytes differentiation.
化学信息
分子量Theoretical: 140 kDa.
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | store at -20°C

计算器

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