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Anti-CD69 Antibody (8U91) 是一种 Rabbit 抗体,靶向 CD69。Anti-CD69 Antibody (8U91) 可用于 ELISA。
Anti-CD69 Antibody (8U91) 是一种 Rabbit 抗体,靶向 CD69。Anti-CD69 Antibody (8U91) 可用于 ELISA。
产品描述 | Anti-CD69 Antibody (8U91) is a Rabbit antibody targeting CD69. Anti-CD69 Antibody (8U91) can be used in ELISA. |
Ig Type | Monoclonal Rabbit IgG |
克隆号 | 8U91 |
交叉反应 | Human |
应用 | ELISA |
推荐剂量 | ELISA: 1:25000-1:50000 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human CD69 (rh CD69; TMPY-01234; NP_001772.1; Ser 62-Lys 199). |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | Early activation antigen CD69, also known as activation inducer molecule (AIM), is a single-pass type II membrane protein. Recently, cDNA clones encoding human and mouse CD69 were isolated and showed CD69 to be a member of the C-type lectin superfamily. It is one of the earliest cell surface antigens expressed by T cells following activation. Once expressed, CD69 acts as a costimulatory molecule for T cell activation and proliferation. In addition to mature T cells, CD69 is inducibly expressed by immature thymocytes, B cells, natural killer (NK) cells, monocytes, neutrophils and eosinophils, and is constitutively expressed by mature thymocytes and platelets. CD69 is involved in lymphocyte proliferation and functions as a signal transmitting receptor in lymphocytes, natural killer (NK) cells, and platelets. The structure, chromosomal localization, expression and function of CD69 suggest that it is likely a pleiotropic immune regulator , potentially important in the activation and differentiation of a wide variety of hematopoietic cells. This membrane molecule transiently expresses on activated lymphocytes, and its selective expression in inflammatory infiltrates suggests that it plays a role in the pathogenesis of inflammatory diseases. CD69 plays a crucial role in the pathogenesis of allergen-induced eosinophilic airway inflammation and hyperresponsiveness and that CD69 could be a possible therapeutic target for asthmatic patients. |
偶联 | Unconjugated |
免疫原 | Recombinant Human CD69 Protein (TMPY-01234) |
抗原种属 | Human |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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