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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-VCP Antibody (9C707)

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货号 TMAB-14061

Anti-VCP Antibody (9C707) 是一种 Mouse 抗体，靶向 VCP。Anti-VCP Antibody (9C707) 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF,FCM。

Anti-VCP Antibody (9C707)

Anti-VCP Antibody (9C707)

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Rating icon 还可以
货号 TMAB-14061

Anti-VCP Antibody (9C707) 是一种 Mouse 抗体，靶向 VCP。Anti-VCP Antibody (9C707) 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF,FCM。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,970
5日内发货
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产品介绍

生物活性
产品描述
Anti-VCP Antibody (9C707) is a Mouse antibody targeting VCP. Anti-VCP Antibody (9C707) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,FCM.
Ig Type
IgG1, k
克隆号
9C707
反应种属
Human,Mouse,Rat
应用WBIHC-PIHC-FrICC/IFIFFCM
推荐剂量
WB: 1:1000-5000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:50-200; IF: 1:100-500; FCM: 1:50-100
抗体种类
Monoclonal
宿主来源Mouse
亚细胞定位Cytoplasm > cytosol. Nucleus. Present in the neuronal hyaline inclusion bodies specifically found in motor neurons from amyotrophic lateral sclerosis patients. Present in the Lewy bodies specifically found in neurons from Parkinson disease patients.
构建方式Hybridoma Monoclonal Antibody
纯化方式Protein G purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The protein encoded by this gene is a member of a family that includes putative ATP-binding proteins involved in vesicle transport and fusion, 26S proteasome function, and assembly of peroxisomes. This protein, as a structural protein, is associated with clathrin, and heat-shock protein Hsc70, to form a complex. It has been implicated in a number of cellular events that are regulated during mitosis, including homotypic membrane fusion, spindle pole body function, and ubiquitin-dependent protein degradation. [provided by RefSeq, Jul 2008]
抗原信息
免疫原
Recombinant Protein: human VCP
抗原种属
Human
基因名称
VCP
基因ID
7415
蛋白名称
Transitional endoplasmic reticulum ATPase
Uniprot ID
P55072
功能
Necessary for the fragmentation of Golgi stacks during mitosis and for their reassembly after mitosis. Involved in the formation of the transitional endoplasmic reticulum (tER). The transfer of membranes from the endoplasmic reticulum to the Golgi apparatus occurs via 50-70 nm transition vesicles which derive from part-rough, part-smooth transitional elements of the endoplasmic reticulum (tER). Vesicle budding from the tER is an ATP-dependent process. The ternary complex containing UFD1L, VCP and NPLOC4 binds ubiquitinated proteins and is necessary for the export of misfolded proteins from the ER to the cytoplasm, where they are degraded by the proteasome. The NPLOC4-UFD1L-VCP complex regulates spindle disassembly at the end of mitosis and is necessary for the formation of a closed nuclear envelope (By similarity). Regulates E3 ubiquitin-protein ligase activity of RNF19A.
化学信息
分子量Theoretical: 97 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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