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顶部生物活性储存和溶解信息计算器

Anti-Caspase-14 Antibody (6X805)

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Anti-Caspase-14 Antibody (6X805)
产品编号 TMAY-02114
别名 caspase 14, apoptosis-related cysteine peptidase, ARCI12

Anti-Caspase-14 Antibody (6X805) 是一种 Rabbit 抗体，靶向 Caspase-14。Anti-Caspase-14 Antibody (6X805) 可用于 IHC-P,ICC/IF。

Anti-Caspase-14 Antibody (6X805)

Anti-Caspase-14 Antibody (6X805)

Rating icon 还可以
Anti-Caspase-14 Antibody (6X805)
产品编号 TMAY-02114 别名 caspase 14, apoptosis-related cysteine peptidase, ARCI12

Anti-Caspase-14 Antibody (6X805) 是一种 Rabbit 抗体，靶向 Caspase-14。Anti-Caspase-14 Antibody (6X805) 可用于 IHC-P,ICC/IF。

规格价格库存数量
100 μL
¥ 2,279
5日内发货
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产品描述
Anti-Caspase-14 Antibody (6X805) is a Rabbit antibody targeting Caspase-14. Anti-Caspase-14 Antibody (6X805) can be used in IHC-P,ICC/IF.
别名caspase 14, apoptosis-related cysteine peptidase, ARCI12
Ig Type
Rabbit IgG
克隆号
6X805
交叉反应
Human
验证活性
1. Immunofluorescence staining of Human CSAP14 in Hela cells. Cells were fixed with 4% PFA, permeabilzed with 1% Triton X-100 in PBS, blocked with 10% serum, and incubated with rabbit anti-Human CASP14 monoclonal antibody (1:60) at 37°C 1 hour. Then cells were stained with the Alexa Fluor® 488-conjugated Goat Anti-rabbit IgG secondary antibody (green) and counterstained with DAPI (blue). Positive staining was localized to cytoplasm and Nucleus.
2. Immunochemical staining of human CASP14 in human skin with rabbit monoclonal antibody (1:300, formalin-fixed paraffin embedded sections).
应用
IHC-P
ICC/IF
推荐剂量
IHC-P: 1:100-1:500; ICC-IF: 1:20-1:100
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Human Caspase-14 / CASP14 (rh Caspase-14 / CASP14; TMPY-01824; NP_036246.1; Ser2-Gln242).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Caspase 14 is a member of the caspase family. Caspases are a kind of cysteine proteinase consisting of a prodomain plus large and small catalytic subunits, that play a central role in cell apoptosis. Caspase 14 possesses an unusually short prodomain and is highly expressed in embryonic tissues but absent from most of the adult tissues except for the skin, which suggests a role in ontogenesis and skin physiology. Unlike the other short prodomain caspases(caspase-3, caspase-6, and caspase-7), Caspase 14 was not processed by multiple death stimuli including activation of members of the tumor necrosis factor receptor family and expression of proapaptotic members of the bcl-2 family. Caspase 14 has been described to be processed and activated by anti-Fas agonist antibody or TNF-related apoptosis inducing ligand in vivo. The expression and processing of this caspase may take part in keratinocyte terminal differentiation, which is essential for the skin barrier.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Human Caspase-14 / CASP14 protein (TMPY-01824)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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关键词

ARCI-12ARCI 12

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