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Anti-RBP4 Antibody (7N540)
还可以产品编号 TMAY-00679
别名 retinol binding protein 4, plasma
Anti-RBP4 Antibody (7N540) 是一种 Mouse 抗体，靶向 RBP4。Anti-RBP4 Antibody (7N540) 可用于 ELISA(Cap)。
Anti-RBP4 Antibody (7N540)
Anti-RBP4 Antibody (7N540)
还可以产品编号 TMAY-00679 别名 retinol binding protein 4, plasma
Anti-RBP4 Antibody (7N540) 是一种 Mouse 抗体，靶向 RBP4。Anti-RBP4 Antibody (7N540) 可用于 ELISA(Cap)。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 20 μL | ¥ 595 | 5日内发货 | |
| 100 μL | ¥ 1,689 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-RBP4 Antibody (7N540) is a Mouse antibody targeting RBP4. Anti-RBP4 Antibody (7N540) can be used in ELISA(Cap). |
| 别名 | retinol binding protein 4, plasma |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 7N540 |
| 交叉反应 | Human |
| 应用 | ELISA(Cap) |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human RBP4 (rh RBP4; TMPY-00907; NP_006735.2; Met1-Leu201). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS with 0.02% Tween 80, pH 7.0 |
| 研究背景 | Retinol-binding protein 4 (RBP4) is the specific carrier for retinol (also known as vitamin A), and is responsible for the conversion of unstable and insoluble retinol in aqueous solution into stable and soluble complex in plasma through their tight interaction. As a member of the lipocalin superfamily, RBP4 containing a β-barrel structure with a well-defined cavity is secreted from the liver, and in turn delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP4-retinol complex interacts with transthyretin (TTR), and this binding is crucial for preventing RBP4 excretion through the kidney glomeruli. RBP4 expressed from an ectopic source efficiently delivers retinol to the eyes, and its deficiency affects night vision largely. Recently, RBP4 as an adipokine, is found to be expressed in adipose tissue and correlated with obesity, insulin resistance (IR) and type 2 diabetes (T2DM). |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human RBP4 Protein (TMPY-00907) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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