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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-KEAP1 Antibody (8I308)

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货号 TMAB-07982

Anti-KEAP1 Antibody (8I308) 是一种 Rabbit 抗体，靶向 KEAP1。Anti-KEAP1 Antibody (8I308) 可用于 WB。

Anti-KEAP1 Antibody (8I308)

Anti-KEAP1 Antibody (8I308)

一键复制产品信息
Rating icon 还可以
货号 TMAB-07982

Anti-KEAP1 Antibody (8I308) 是一种 Rabbit 抗体，靶向 KEAP1。Anti-KEAP1 Antibody (8I308) 可用于 WB。

规格价格库存数量
25 μL
¥ 780
5日内发货
50 μL
¥ 1,380
5日内发货
100 μL
¥ 2,490
5日内发货
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产品介绍

生物活性
产品描述
Anti-KEAP1 Antibody (8I308) is a Rabbit antibody targeting KEAP1. Anti-KEAP1 Antibody (8I308) can be used in WB.
Ig Type
IgG
克隆号
8I308
反应种属
Human
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Nucleus. Note=Shuttles between cytoplasm and nucleus.
组织特异性Broadly expressed, with highest levels in skeletal muscle.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene. [provided by RefSeq, Jul 2008].
抗原信息
免疫原
KLH conjugated synthetic peptide: human KEAP1
抗原种属
Human
基因名称
KEAP1
基因ID
9817
蛋白名称
Kelch-like ECH-associated protein 1
Uniprot ID
Q14145
功能
Retains NFE2L2/NRF2 in the cytosol. Functions as substrate adapter protein for the E3 ubiquitin ligase complex formed by CUL3 and RBX1. Targets NFE2L2/NRF2 for ubiquitination and degradation by the proteasome, thus resulting in the suppression of its transcriptional activity and the repression of antioxidant response element-mediated detoxifying enzyme gene expression. May also retain BPTF in the cytosol. Targets PGAM5 for ubiquitination and degradation by the proteasome.
化学信息
分子量Theoretical: 69 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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