购物车
- 全部删除
您的购物车当前为空
Anti-EDA2R Antibody (8P889)
还可以产品编号 TMAY-02092
Anti-EDA2R Antibody (8P889) 是一种 Mouse 抗体，靶向 EDA2R。Anti-EDA2R Antibody (8P889) 可用于 ELISA。
Anti-EDA2R Antibody (8P889)
Anti-EDA2R Antibody (8P889)
还可以产品编号 TMAY-02092
Anti-EDA2R Antibody (8P889) 是一种 Mouse 抗体，靶向 EDA2R。Anti-EDA2R Antibody (8P889) 可用于 ELISA。
产品信息正在更新中，如果您想购买，请点击大包装&定制按钮.
大包装 & 定制
联系我们获取更多批次信息
资源下载
产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-EDA2R Antibody (8P889) is a Mouse antibody targeting EDA2R. Anti-EDA2R Antibody (8P889) can be used in ELISA. |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 8P889 |
| 交叉反应 | Human |
| 应用 | ELISA |
| 推荐剂量 | ELISA: 1:1000-1:2000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human XEDAR / EDA2R (rh XEDAR / EDA2R; TMPY-01932; NP_068555.1; Met 1-Thr 138). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Tumor necrosis factor receptor superfamily member 27, also known as X-linked ectodysplasin-A2 receptor, EDA-A2 receptor, EDA2R, XEDAR and TNFRSF27, is a single-pass type III membrane protein. TNFRSF27 / EDA2R contains threeTNFR-Cys repeats. It is a new member of the tumor necrosis factor receptor family that has been shown to be highly expressed in ectodermal derivatives during embryonic development and binds to ectodysplasin-A2 (EDA-A2). TNFRSF27 / EDA2R is a receptor for EDA isoform A2, but not for EDA isoform A1. TNFRSF27 / EDA2R mediates the activation of the NF-kappa-B and JNK pathways. The activation seems to be mediated by binding to TRAF3 and TRAF6. Ectodysplasin, a member of the tumor necrosis factor family, is encoded by the anhidrotic ectodermal dysplasia EDA gene. Mutations in EDA give rise to a clinical syndrome characterized by loss of hair, sweat glands, and teeth. EDA-A1 and EDA-A2 are two isoforms of ectodysplasin that differ only by an insertion of two amino acids. This insertion functions to determine receptor binding specificity, such that EDA-A1 binds only the receptor EDAR, whereas EDA-A2 binds only the related, but distinct, X-linked ectodysplasin-A2 receptor (XEDAR). |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human XEDAR / EDA2R protein (TMPY-01932) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
SCI 文献
计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
评论列表
预览
Related Tags: buy Anti-EDA2R Antibody (8P889) | purchase Anti-EDA2R Antibody (8P889) | Anti-EDA2R Antibody (8P889) cost | order Anti-EDA2R Antibody (8P889)
嗨！有任何问题？点我咨询
评论内容