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Anti-RING2 Antibody (5I450) 是一种 Rabbit 抗体,靶向 RING2。Anti-RING2 Antibody (5I450) 可用于 WB,IHC。
Anti-RING2 Antibody (5I450) 是一种 Rabbit 抗体,靶向 RING2。Anti-RING2 Antibody (5I450) 可用于 WB,IHC。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,490 | 5日内发货 | |
100 μL | ¥ 2,485 | 5日内发货 |
产品描述 | Anti-RING2 Antibody (5I450) is a Rabbit antibody targeting RING2. Anti-RING2 Antibody (5I450) can be used in WB,IHC. |
别名 | Rnf2, RNF 2, RING2_HUMAN, RING1b, RING finger protein BAP-1, RING finger protein BAP1, RING finger protein BAP 1, RING finger protein 2, RING finger protein 1B, RING 2, RING 1B, Protein DinG, Polycomb M33 interacting protein Ring1B, Polycomb M33 interacting protein Ring 1B, OTTHUMP00000060668, Huntingtin-interacting protein 2-interacting protein 3, Huntingtin interacting protein 2 interacting protein 3, HIPI3, HIPI 3, HIP2-interacting protein 3, HIP2 interacting protein 3, E3 ubiquitin-protein ligase RING2, E3 ubiquitin protein ligase RING2, E3 ubiquitin protein ligase RING 2, DinG protein, DING, BAP1, BAP 1 |
Ig Type | IgG |
交叉反应 | Human,Mouse,Rat |
验证活性 | 1. Western blot analysis of RING2 on k562 cell using anti-RING2 antibody at 1/500 dilution. 2. Immunohistochemical analysis of paraffin-embedded human placenta tissue using anti-RING2 antibody. Counter stained with hematoxylin. |
应用 | |
推荐剂量 | WB: 1:500-1000; IHC: 1:50-200 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | Recombinant Antibody |
纯化方式 | ProA affinity purified |
性状 | Liquid |
缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
研究背景 | E3 ubiquitin-protein ligase that mediates monoubiquitination of 'Lys-119' of histone H2A (H2AK119Ub), thereby playing a central role in histone code and gene regulation. H2AK119Ub gives a specific tag for epigenetic transcriptional repression and participates in X chromosome inactivation of female mammals. May be involved in the initiation of both imprinted and random X inactivation. Essential component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, rendering chromatin heritably changed in its expressibility. E3 ubiquitin-protein ligase activity is enhanced by BMI1/PCGF4. Acts as the main E3 ubiquitin ligase on histone H2A of the PRC1 complex, while RING1 may rather act as a modulator of RNF2/RING2 activity (Probable). |
偶联 | Unconjugated |
免疫原 | Recombinant Protein |
Uniprot ID |
分子量 | Theoretical: 38 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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