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Anti-CCL19/MIP-3b Antibody (4C246)
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产品编号 TMAH-00149
别名 Scya19, MIP3B, exodus-3, ELC, CKb11, chemokine (C-C motif) ligand 19
Anti-CCL19/MIP-3b Antibody (4C246) 是一种抗体，靶向 CCL19/MIP-3b。Anti-CCL19/MIP-3b Antibody (4C246) 可用于 ELISA, IHC。
Anti-CCL19/MIP-3b Antibody (4C246)
Anti-CCL19/MIP-3b Antibody (4C246)
还可以产品编号 TMAH-00149 别名 Scya19, MIP3B, exodus-3, ELC, CKb11, chemokine (C-C motif) ligand 19
Anti-CCL19/MIP-3b Antibody (4C246) 是一种抗体，靶向 CCL19/MIP-3b。Anti-CCL19/MIP-3b Antibody (4C246) 可用于 ELISA, IHC。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,305 | 5日内发货 | |
| 100 μL | ¥ 2,195 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-CCL19/MIP-3b Antibody (4C246) is an antibody targeting CCL19/MIP-3b. Anti-CCL19/MIP-3b Antibody (4C246) can be used in ELISA, IHC. |
| 别名 | Scya19, MIP3B, exodus-3, ELC, CKb11, chemokine (C-C motif) ligand 19 |
| Ig Type | Rabbit IgG |
| 克隆号 | 4C246 |
| 交叉反应 | Human |
| 验证活性 | 1. IHC image of TMAH-00149 diluted at 1:155 and staining in paraffin-embedded human tonsil tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. 2. IHC image of TMAH-00149 diluted at 1:155 and staining in paraffin-embedded human appendix tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
| 应用 | |
| 推荐剂量 | IHC:1:50-1:200. |
| 抗体种类 | Monoclonal |
| 亚细胞定位 | Secreted. |
| 组织特异性 | Expressed at high levels in the lymph nodes, thymus and appendix. Intermediate levels seen in colon and trachea, while low levels found in spleen, small intestine, lung, kidney and stomach. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Affinity-chromatography |
| 性状 | Liquid |
| 缓冲液 | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| 研究背景 | May play a role not only in inflammatory and immunological responses but also in normal lymphocyte recirculation and homing. May play an important role in trafficking of T-cells in thymus, and T-cell and B-cell migration to secondary lymphoid organs. Binds to chemokine receptor CCR7. Recombinant CCL19 shows potent chemotactic activity for T-cells and B-cells but not for granulocytes and monocytes. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4. |
| 偶联 | Unconjugated |
| 免疫原 | A synthetic peptide: Human CCL19 |
| 抗原种属 | Human |
| 基因名称 | CCL19 |
| 基因ID | |
| Uniprot ID | |
| 研究领域 | Immunology |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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