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Anti-OCLN Antibody (1S954)

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Anti-OCLN Antibody (1S954)
产品编号 TMAC-02912
别名 Tight junction protein occludin, Occludin1, Occludin, Occludin-1, Occludin, MGC34277, FLJ94056, FLJ77961, FLJ18079, FLJ08163, BLCPMG

Anti-OCLN Antibody (1S954) 是一种 Rabbit 抗体,靶向 OCLN。Anti-OCLN Antibody (1S954) 可用于 WB,IP,FCM。

Anti-OCLN Antibody (1S954)

Anti-OCLN Antibody (1S954)

Rating icon 还可以
Anti-OCLN Antibody (1S954)
产品编号 TMAC-02912 别名 Tight junction protein occludin, Occludin1, Occludin, Occludin-1, Occludin, MGC34277, FLJ94056, FLJ77961, FLJ18079, FLJ08163, BLCPMG

Anti-OCLN Antibody (1S954) 是一种 Rabbit 抗体,靶向 OCLN。Anti-OCLN Antibody (1S954) 可用于 WB,IP,FCM。

规格价格库存数量
50 μL
¥ 1,490
5日内发货
100 μL
¥ 2,495
5日内发货
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产品介绍

生物活性
产品描述
Anti-OCLN Antibody (1S954) is a Rabbit antibody targeting OCLN. Anti-OCLN Antibody (1S954) can be used in WB,IP,FCM.
别名Tight junction protein occludin, Occludin1, Occludin, Occludin-1, Occludin, MGC34277, FLJ94056, FLJ77961, FLJ18079, FLJ08163, BLCPMG
Ig Type
IgG
交叉反应
Human,Mouse,Rat
验证活性
1. Flow cytometric analysis of 293 cells with Occludin antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody.
2. All lanes use the Antibody at 1:1000 dilution for 1 hour at room temperature.
3. All lanes use the Antibody at 1:1000 dilution for 1 hour at room temperature.
4. All lanes use the Antibody at 1:1000 dilution for 1 hour at room temperature.
应用
推荐剂量
WB: 1:1000; FCM: 1:50-100
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景Occludin is an integral membrane protein closely associated with the tight junctions of epithelial and endothelial cells. Occludin is a tetraspan integral membrane protein in epithelial and endothelial tight junction (TJ) structures that can contain two extracellular loops. The protein exists in a variety of phosphorylated forms. Phosphorylation is involved in regulating both the localization and the function of occludin. Expression of occludin is up-regulated by poly-unsaturated fatty acids, increasing transendothelial cell resistance and reducing cellular permeability to large molecules. The level of occludin varies greatly depending on tissue; in brain tissue, occludin is highly expressed at cell-cell contact sites. Non-neural tissues show lower expression and discontinuous distribution. Up-regulation of epithelial occludin may play a role in enhancing paracellular permeability and be related to the damage to the tight junction.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
化学信息
分子量Theoretical: 59 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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