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Anti-Neprilysin/CD10 Antibody (8D161)
还可以产品编号 TMAY-00146
别名 SFE, NEP, membrane metallo-endopeptidase, CD10, CALLA
Anti-Neprilysin/CD10 Antibody (8D161) 是一种 Rabbit 抗体，靶向 Neprilysin/CD10。Anti-Neprilysin/CD10 Antibody (8D161) 可用于 ICC/IF。
Anti-Neprilysin/CD10 Antibody (8D161)
Anti-Neprilysin/CD10 Antibody (8D161)
还可以产品编号 TMAY-00146 别名 SFE, NEP, membrane metallo-endopeptidase, CD10, CALLA
Anti-Neprilysin/CD10 Antibody (8D161) 是一种 Rabbit 抗体，靶向 Neprilysin/CD10。Anti-Neprilysin/CD10 Antibody (8D161) 可用于 ICC/IF。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 100 μL | ¥ 2,279 | 5日内发货 |
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产品介绍
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偶联与修饰
抗原信息
| 产品描述 | Anti-Neprilysin/CD10 Antibody (8D161) is a Rabbit antibody targeting Neprilysin/CD10. Anti-Neprilysin/CD10 Antibody (8D161) can be used in ICC/IF. |
| 别名 | SFE, NEP, membrane metallo-endopeptidase, CD10, CALLA |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 8D161 |
| 交叉反应 | Human |
| 验证活性 | Immunofluorescence staining of MME in MCF7 cells. Cells were fixed with 4% PFA,blocked with 10% serum, and incubated with rabbit anti-human MME monoclonal antibody (dilution ratio 1:60) at 4°C overnight. Then cells were stained with the Alexa Fluor®488-conjugated Goat Anti-rabbit IgG secondary antibody (green). Positive staining was localized to Cell membrane. |
| 应用 | ICC/IF |
| 推荐剂量 | ICC-IF: 1:20-1:100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with a synthetic peptide corresponding to the center region of the Human CD10/Neprilysin/MME. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alters the behavior of the cell. Some CD proteins do not take part in the cell signal process but have other functions such as cell adhesion. The cluster of differentiation 10 (CD10), also known as Neprilysin and neutral endopeptidase, is a member of the CD system. CD10 is a zinc-dependent metalloprotease enzyme that had the function to degrade some small secreted peptides such as the amyloid beta-peptide. It exists as a membrane-bound protein and has a high concentration in kidney and lung tissues. Mutations in the CD10 gene can induce the familial forms of Alzheimer's disease, providing strong evidence for the protein's association with the Alzheimer's disease process. CD10 is also associated with other biochemical processes. |
| 偶联 | Unconjugated |
| 免疫原 | A synthetic peptide corresponding to the center region of the Human CD10/Neprilysin/MME |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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