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Anti-Perilipin 1 Polyclonal Antibody

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货号 TMAB-10187

Anti-Perilipin 1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Perilipin 1。Anti-Perilipin 1 Polyclonal Antibody 可用于 WB,FCM。

Anti-Perilipin 1 Polyclonal Antibody

Anti-Perilipin 1 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-10187

Anti-Perilipin 1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Perilipin 1。Anti-Perilipin 1 Polyclonal Antibody 可用于 WB,FCM。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-Perilipin 1 Polyclonal Antibody is a Rabbit antibody targeting Perilipin 1. Anti-Perilipin 1 Polyclonal Antibody can be used in WB,FCM.
Ig Type
IgG
反应种属
Mouse,Rat (predicted:Human,Pig,Cow,Sheep)
应用WBFCM
推荐剂量
WB: 1:500-2000; FCM: 5μg/Test
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Lipid droplet. Note=Lipid droplet surface-associated.
组织特异性Adipocytes.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Perilipins, members of the PAT protein family (named after lipid droplet proteins Perilipin, Adipophilin, and TIP47) are found exclusively at the surface of lipid droplets in adipocytes and steroidogenic cells. They have been suggested to function as regulators of lipolysis and triacylglycerol storage within adipose tissue. Four distinct isoforms ranging from perilipin A (57 kDa) to perilipin D (26 kDa) have been identified and they share an identical amino terminal sequences, and contain 2–6 consensus protein kinase A (PKA) phosphorylation sites. Perilipin C and D have been detected only in steroidogenic cells. Perilipin A is the most abundant form on the lipid droplets of adipocytes. The phosphorylation of perilipin by PKA, which is accompanied by the phosphorylation and translocation of hormone-sensitive lipase from the cytosol to the lipid droplets, promotes lipolysis. There is evidence for the presence of perilipin A in atheroma plaques suggesting that the protein may be involved in the development of therosclerosis by controlling as in adipocytes the hydrolysis of stored lipids.
抗原信息
免疫原
KLH conjugated synthetic peptide: human Perilipin-1
抗原种属
Human
基因名称
PLIN1
基因ID
5346
蛋白名称
Perilipin
Uniprot ID
O60240
功能
Modulator of adipocyte lipid metabolism. Coats lipid storage droplets to protect them from breakdown by hormone-sensitive lipase (HSL). Its absence may result in leanness.
化学信息
分子量Theoretical: 57 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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