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Anti-Phospho-LATS1/2 (Thr1079/1041) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-LATS1/2 (Thr1079/1041)。Anti-Phospho-LATS1/2 (Thr1079/1041) Polyclonal Antibody 可用于 IHC。
Anti-Phospho-LATS1/2 (Thr1079/1041) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-LATS1/2 (Thr1079/1041)。Anti-Phospho-LATS1/2 (Thr1079/1041) Polyclonal Antibody 可用于 IHC。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,490 | 5日内发货 | |
100 μL | ¥ 2,240 | 5日内发货 |
产品描述 | Anti-Phospho-LATS1/2 (Thr1079/1041) Polyclonal Antibody is a Rabbit antibody targeting Phospho-LATS1/2 (Thr1079/1041). Anti-Phospho-LATS1/2 (Thr1079/1041) Polyclonal Antibody can be used in IHC. |
别名 | p-LATS1/2 (Thr1079/1041), p-LATS1/2 (T1079/1041), LATS1/2 (p-Thr1079/1041), LATS1/2 (p-T1079/1041) |
Ig Type | IgG |
交叉反应 | Human,Mouse |
验证活性 | 1. Immunohistochemical analysis of paraffin-embedded human brain tissue using LATS1/2 (Phospho-Thr1079/1041) antibody TMAC-02375 (left) or the same antibody preincubated with blocking peptide (right). |
应用 | |
推荐剂量 | IHC: 1:50-100 |
抗体种类 | Polyclonal |
宿主来源 | Rabbit |
构建方式 | Polyclonal Antibody |
纯化方式 | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
性状 | Liquid |
缓冲液 | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
研究背景 | The protein encoded by this gene is a putative serine/threonine kinase that localizes to the mitotic apparatus and complexes with cell cycle controller CDC2 kinase in early mitosis. The protein is phosphorylated in a cell-cycle dependent manner, with late prophase phosphorylation remaining through metaphase. The N-terminal region of the protein binds CDC2 to form a complex showing reduced H1 histone kinase activity, indicating a role as a negative regulator of CDC2/cyclin A. In addition, the C-terminal kinase domain binds to its own N-terminal region, suggesting potential negative regulation through interference with complex formation via intramolecular binding. |
偶联 | Unconjugated |
其他可选修饰符 | Phospho |
免疫原 | Peptide sequence around phosphorylation site of threonine 1079/1041 (E-F-T(p)-F-R) derived from Human LATS1/2 |
抗原种属 | human |
Uniprot ID |
分子量 | Actual: 126 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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