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Anti-TLR2 Antibody-FITC (3U29)

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产品编号 TMAY-00203F
别名 toll-like receptor 2

Anti-TLR2 Antibody-FITC (3U29) 是一种 FITC-conjugated Rabbit 抗体,靶向 TLR2。Anti-TLR2 Antibody-FITC (3U29) 可用于 FCM。

Anti-TLR2 Antibody-FITC (3U29)

Anti-TLR2 Antibody-FITC (3U29)

Rating icon 还可以
产品编号 TMAY-00203F 别名 toll-like receptor 2

Anti-TLR2 Antibody-FITC (3U29) 是一种 FITC-conjugated Rabbit 抗体,靶向 TLR2。Anti-TLR2 Antibody-FITC (3U29) 可用于 FCM。

规格价格库存数量
25 T
¥ 890
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100 T
¥ 2,185
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产品介绍

生物活性
产品描述
Anti-TLR2 Antibody-FITC (3U29) is a FITC-conjugated Rabbit antibody targeting TLR2. Anti-TLR2 Antibody-FITC (3U29) can be used in FCM.
别名toll-like receptor 2
Ig Type
Monoclonal Rabbit IgG
克隆号
3U29
交叉反应
Human
验证活性
Flow cytometric analysis of Human TLR2(CD282) expression on human whole blood monocytes. Cells were stained with FITC-conjugated anti-Human TLR2(CD282). The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable monocytes.
应用
FCM
推荐剂量
10 μl/Test, 0.1 mg/ml
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Human TLR2/CD282 (rh TLR2/CD282; NP_003255.2Met1-Arg587) and conjugated with FITC under optimum conditions, the unreacted FITC was removed.
纯化方式Protein A
性状Liquid
缓冲液PBS solution containing 0.5% BSA and 0.09% sodium azide
研究背景TLR2, also known as CD282, is a member of the Toll-like receptor (TLR) family. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They play a fundamental role in pathogen recognition and activation of innate immunity. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. TLR2 contains 14 LRR (leucine-rich) repeats and 1 TIR domain. TLR2 gene is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB. CD282 cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. It also cooperates with TLR1 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. CD282 acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. It may also promote apoptosis in response to lipoproteins.
偶联与修饰
偶联
FITC
其他可选修饰符
Unconjugated/APC/Biotin/PE
可提供抗体种类
5
抗原信息
免疫原
Recombinant Human TLR2/CD282 Protein
抗原种属
Human
研究领域
Neuroinflammation
存储&运输
储存方式Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal.
运输方式Shipping with blue ice.

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