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Anti-Carbonic Anhydrase VB Antibody (3I792)
还可以产品编号 TMAY-02314
Anti-Carbonic Anhydrase VB Antibody (3I792) 是一种 Rabbit 抗体，靶向 Carbonic Anhydrase VB。Anti-Carbonic Anhydrase VB Antibody (3I792) 可用于 IHC-P。
Anti-Carbonic Anhydrase VB Antibody (3I792)
Anti-Carbonic Anhydrase VB Antibody (3I792)
还可以产品编号 TMAY-02314
Anti-Carbonic Anhydrase VB Antibody (3I792) 是一种 Rabbit 抗体，靶向 Carbonic Anhydrase VB。Anti-Carbonic Anhydrase VB Antibody (3I792) 可用于 IHC-P。
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抗原信息
| 产品描述 | Anti-Carbonic Anhydrase VB Antibody (3I792) is a Rabbit antibody targeting Carbonic Anhydrase VB. Anti-Carbonic Anhydrase VB Antibody (3I792) can be used in IHC-P. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 3I792 |
| 交叉反应 | Human |
| 验证活性 | 1. Immunochemical staining of human CA5B in human placenta with rabbit monoclonal antibody (1:100, formalin-fixed paraffin embedded sections). 2. Immunochemical staining of human CA5B in human lung with rabbit monoclonal antibody (1:100, formalin-fixed paraffin embedded sections). 3. Immunochemical staining of human CA5B in human kidney with rabbit monoclonal antibody (1:100, formalin-fixed paraffin embedded sections). |
| 应用 | IHC-P |
| 推荐剂量 | IHC-P: 1:50-1:200 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human Carbonic Anhydrase VB / CA5B (rh Carbonic Anhydrase VB / CA5B; TMPY-02133; Q9Y2D0; Cys34-Pro317). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Carbonic anhydrase 5B, also known as carbonate dehydratase VB, carbonic anhydrase VB, CA-VB and CA5B, is amember of the alpha-carbonic anhydrase family. The strongest expression of CA5B / CA-VB is in heart, pancreas, kidney, placenta, lung, and skeletal muscle. It is not expressed in liver. Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes first discovered in 1933 that catalyze the reversible hydration of carbon dioxide. CAs participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. CAs show extensive diversity in tissue distribution and in their subcellular localization. CA5B / CA-VB is localized in the mitochondria and shows the highest sequence similarity to the other mitochondrial CA5A / CA-VA. CA5B / CA-VB has a wider tissue distribution than CA5A / CA-VA, which is restricted to the liver. The differences in tissue distribution suggest that the two mitochondrial carbonic anhydrases evolved to assume different physiologic roles. CA5A / CA-VA is activated by histamine, L-adrenaline, L- and D-histidine, and L- and D-phenylalanine. It is inhibited by coumarins, sulfonamide derivatives such as acetazolamide and Foscarnet (phosphonoformate trisodium salt). CA5B / CA-VB is inhibited by coumarins, sulfonamide derivatives such as acetazolamide (AZA), saccharin and Foscarnet (phosphonoformate trisodium salt). |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human Carbonic Anhydrase VB / CA5B protein (TMPY-02133) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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