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Anti-CK18 Antibody (2A807) 是一种 Mouse 抗体,靶向 CK18。Anti-CK18 Antibody (2A807) 可用于 IHC-P,IHC-Fr,IF。
Anti-CK18 Antibody (2A807) 是一种 Mouse 抗体,靶向 CK18。Anti-CK18 Antibody (2A807) 可用于 IHC-P,IHC-Fr,IF。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 3 mL | ¥ 550 | 5日内发货 | |
| 6 mL | ¥ 970 | 5日内发货 |
| 产品描述 | Anti-CK18 Antibody (2A807) is a Mouse antibody targeting CK18. Anti-CK18 Antibody (2A807) can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| 克隆号 | 2A807 |
| 反应种属 | Human |
| 应用 | IHC-PIHC-FrIF |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 亚细胞定位 | Cytoplasm, perinuclear region. Nucleus, nucleolus. |
| 组织特异性 | Expressed in colon, placenta, liver and very weakly in exocervix. Increased expression observed in lymph nodes of breast carcinoma. |
| 构建方式 | Hybridoma Monoclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M PBS (pH7.4) with 1% BSA and 0.02% Proclin300. |
| 研究背景 | KRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008] |
| 免疫原 | KLH conjugated synthetic peptide: human CK18 |
| 抗原种属 | Human |
| 基因名称 | KRT18 |
| 基因ID | |
| 蛋白名称 | Keratin, type I cytoskeletal 18 |
| Uniprot ID | |
| 功能 | When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Involved in the uptake of thrombin-antithrombin complexes by hepatic cells (By similarity). Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection. |
| 分子量 | Theoretical: 48 kDa. |
| 储存方式 | Store at 2°C-8°C for 12 months, do not freeze. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |