Name: Anti-Mouse TIM-1/CD365 Antibody (3D10)
Brand: TargetMol
SKU: T9901A-177
Rating: 4.5 (1 reviews)

规格

价格

库存

数量

1 mg

待询

现货

5 mg

待询

生物活性

产品描述	Anti-Mouse TIM-1/CD365 Antibody (3D10) is a rat-derived monoclonal antibody that specifically binds to and blocks T-cell immunoglobulin and mucin domain-containing protein 1 (TIM-1). Anti-Mouse TIM-1/CD365 Antibody (3D10) is primarily used for functional blocking experiments both in vivo and in vitro. Anti-Mouse TIM-1/CD365 Antibody (3D10) exhibits dual regulatory effects in vivo: it exacerbates lesion development in atherosclerosis models while effectively reducing disease severity in graft-versus-host disease (GVHD) models.
体内活性	Anti-Mouse TIM-1/CD365 Antibody (3D10)(200 μg，腹腔注射，每周两次，持续 4 周)在高脂饮食的ldlr−/−小鼠中与抗Tim-4抗体联合使用会加剧动脉粥样硬化的发展[1]。 Anti-Mouse TIM-1/CD365 Antibody (3D10)(臭氧暴露前24小时给药)可预防野生型小鼠中臭氧诱导的气道高反应性和气道炎症[2]。 Anti-Mouse TIM-1/CD365 Antibody (3D10)(400 μg，腹腔注射，在第-1、3、7、11和17天给药) 可预防接受同种异体B6骨髓和Tcon细胞(H-2b)的致死性照射BALB/c(H-2d)小鼠发生移植物抗宿主病(GVHD)[3]。
别名	抗-小鼠 TIM-1/CD365 抗体(3D10)
克隆号	3D10
反应种属	Mouse
应用	ELISA FACS Functional assay
抗体种类	Monoclonal
缓冲液	Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
内毒素	<1.0 EU/mg

偶联与修饰

偶联	Unconjugated

抗原信息

靶点	TIM-1/CD365

储存&溶解度

存储	Store at low temperature -20°C for 1 year Shipping with blue ice/Shipping at ambient temperature. 实际储存温度请以COA为准

Anti-Mouse TIM-1/CD365 Antibody (3D10)