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Anti-Phospho-SMC1A (Ser957) Polyclonal Antibody

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Anti-Phospho-SMC1A (Ser957) Polyclonal Antibody
产品编号 TMAC-03805
别名 SMC1A (p-Ser957), SMC1A (p-S957), p-SMC1A (Ser957), p-SMC1A (S957)

Anti-Phospho-SMC1A (Ser957) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-SMC1A (Ser957)。Anti-Phospho-SMC1A (Ser957) Polyclonal Antibody 可用于 WB,IHC。

Anti-Phospho-SMC1A (Ser957) Polyclonal Antibody

Anti-Phospho-SMC1A (Ser957) Polyclonal Antibody

Rating icon 还可以
Anti-Phospho-SMC1A (Ser957) Polyclonal Antibody
产品编号 TMAC-03805 别名 SMC1A (p-Ser957), SMC1A (p-S957), p-SMC1A (Ser957), p-SMC1A (S957)

Anti-Phospho-SMC1A (Ser957) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-SMC1A (Ser957)。Anti-Phospho-SMC1A (Ser957) Polyclonal Antibody 可用于 WB,IHC。

规格价格库存数量
50 μL
¥ 1,485
5日内发货
100 μL
¥ 2,245
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-SMC1A (Ser957) Polyclonal Antibody is a Rabbit antibody targeting Phospho-SMC1A (Ser957). Anti-Phospho-SMC1A (Ser957) Polyclonal Antibody can be used in WB,IHC.
别名SMC1A (p-Ser957), SMC1A (p-S957), p-SMC1A (Ser957), p-SMC1A (S957)
Ig Type
IgG
交叉反应
Human
验证活性
1. Western blot analysis of extracts from 293 cells untreated or treated with UV using SMC1 (Phospho-Ser957) Antibody TMAC-03805.
2. Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using SMC1 (Phospho-Ser957) Antibody TMAC-03805 (left) or the same antibody preincubated with blocking peptide (right).
应用
抗体种类
Polyclonal
宿主来源Rabbit
构建方式Polyclonal Antibody
纯化方式Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
性状Liquid
缓冲液Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
研究背景Involved in chromosome cohesion during cell cycle and in DNA repair. Central component of cohesin complex. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis. Involved in DNA repair via its interaction with BRCA1 and its related phosphorylation by ATM, or via its phosphorylation by ATR. Works as a downstream effector both in the ATM/NBS1 branch and in the ATR/MSH2 branch of S-phase checkpoint.
偶联与修饰
偶联
Unconjugated
其他可选修饰符
Phospho
抗原信息
免疫原
Peptide sequence around phosphorylation site of serine 957 (G-S-S(p)-Q-G) derived from Human SMC1
抗原种属
human
Uniprot ID
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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